Role of phosphorylation and basic residues in the catalytic domain of cytosolic phospholipase A2alpha in regulating interfacial kinetics and binding and cellular function.
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Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionFunctional characterization of mutations in inherited human cPLA₂ deficiencyCeramide 1-phosphate is required for the translocation of group IVA cytosolic phospholipase A2 and prostaglandin synthesis.Localization and function of cytosolic phospholipase A2alpha at the Golgi.Pathways regulating cytosolic phospholipase A2 activation and eicosanoid production in macrophages by Candida albicansInterfacial kinetic and binding properties of mammalian group IVB phospholipase A2 (cPLA2beta) and comparison with the other cPLA2 isoforms.Astrocyte inositol triphosphate receptor type 2 and cytosolic phospholipase A2 alpha regulate arteriole responses in mouse neocortical brain slices.Protease-activated receptor signaling in platelets activates cytosolic phospholipase A2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis.Targeting cytosolic phospholipase A2 α in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation.Cytosolic phospholipase A₂: physiological function and role in disease.Phospholipase A2IVα regulates phagocytosis independent of its enzymatic activityTargeting of cytosolic phospholipase A2α impedes cell cycle re-entry of quiescent prostate cancer cells.Prostaglandins from Cytosolic Phospholipase A2α/Cyclooxygenase-1 Pathway and Mitogen-activated Protein Kinases Regulate Gene Expression in Candida albicans-infected Macrophages.The molecular basis of ceramide-1-phosphate recognition by C2 domains.Phospholipases A2 and inflammatory responses in the central nervous system.Janus kinase 3 activity is necessary for phosphorylation of cytosolic phospholipase A2 and prostaglandin E2 synthesis by macrophages infected with Francisella tularensis live vaccine strain.Lactosylceramide-Induced Phosphorylation Signaling to Group IVA Phospholipase A2 via Reactive Oxygen Species in Tumor Necrosis Factor-α-Treated Cells.Loss of PTEN stabilizes the lipid modifying enzyme cytosolic phospholipase A₂α via AKT in prostate cancer cells.C2 domain membrane penetration by group IVA cytosolic phospholipase A₂ induces membrane curvature changes.The cationic cluster of group IVA phospholipase A2 (Lys488/Lys541/Lys543/Lys544) is involved in translocation of the enzyme to phagosomes in human macrophages.Off-target effect of the cPLA2α inhibitor pyrrophenone: Inhibition of calcium release from the endoplasmic reticulumLactosylceramide interacts with and activates cytosolic phospholipase A2α.Effects of unsaturated fatty acids on the kinetics of voltage-gated proton channels heterologously expressed in cultured cells.
P2860
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P2860
Role of phosphorylation and basic residues in the catalytic domain of cytosolic phospholipase A2alpha in regulating interfacial kinetics and binding and cellular function.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 28 January 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Role of phosphorylation and ba ...... binding and cellular function.
@en
Role of phosphorylation and ba ...... binding and cellular function.
@nl
type
label
Role of phosphorylation and ba ...... binding and cellular function.
@en
Role of phosphorylation and ba ...... binding and cellular function.
@nl
prefLabel
Role of phosphorylation and ba ...... binding and cellular function.
@en
Role of phosphorylation and ba ...... binding and cellular function.
@nl
P2093
P2860
P356
P1476
Role of phosphorylation and ba ...... binding and cellular function.
@en
P2093
Bonnie St John
Christina C Leslie
Dawn E Tucker
Farideh Ghomashchi
James G Bollinger
Milena Girotti
Moumita Ghosh
Robyn Loper
Saritha Suram
P2860
P304
P356
10.1074/JBC.M807299200
P407
P577
2009-01-28T00:00:00Z