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Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathwaysWW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancerIncreasing the relative expression of endogenous non-coding Steroid Receptor RNA Activator (SRA) in human breast cancer cells using modified oligonucleotidesThe NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor geneTargeting γ-secretase in breast cancerProteolytic Processing of ErbB4 in Breast CancerNuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer.Cell death or survival promoted by alternative isoforms of ErbB4Overexpression of c-erbB2 is a negative prognostic factor in anaplastic astrocytomas.ERBB4 promoter polymorphism is associated with poor distant disease-free survival in high-risk early breast cancerThe localization of HER4 intracellular domain and expression of its alternately-spliced isoforms have prognostic significance in ER+ HER2- breast cancer.Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention.Quantitative proteomics with siRNA screening identifies novel mechanisms of trastuzumab resistance in HER2 amplified breast cancers.EGFR signaling in breast cancer: bad to the bone.E3 ubiquitin ligases in ErbB receptor quantity control.Reactivation of epigenetically silenced HER4/ERBB4 results in apoptosis of breast tumor cells.Breast cancer subtyping from plasma proteins.copy number variation analysis in familial BRCA1/2-negative Finnish breast and ovarian cancer.The prognostic value of Her4 receptor isoform expression in triple-negative and Her2 positive breast cancer patients.Mining the tissue-tissue gene co-expression network for tumor microenvironment study and biomarker prediction.Expression of the EGF family in gastric cancer: downregulation of HER4 and its activating ligand NRG4.The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility.ErbB2 Is Necessary for ErbB4 Ligands to Stimulate Oncogenic Activities in Models of Human Breast Cancer.Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signalingPrognostic value of ERBB4 expression in patients with triple negative breast cancerNeuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration.Neuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptakeDecreased LRIG1 in fulvestrant-treated luminal breast cancer cells permits ErbB3 upregulation and increased growth.HER4 intracellular domain (4ICD) activity in the developing mammary gland and breast cancer.Aberrant expression of DNA damage response proteins is associated with breast cancer subtype and clinical featuresBiological function of nuclear receptor tyrosine kinase action.Roles of the WWOX in pathogenesis and endocrine therapy of breast cancer.ErbB3 downregulation enhances luminal breast tumor response to antiestrogens.Immunohistochemical characterization of subtypes of male breast carcinoma.Presence of HER4 associates with increased sensitivity to Herceptin in patients with metastatic breast cancer.Subcellular localization of the HER4 intracellular domain, 4ICD, identifies distinct prognostic outcomes for breast cancer patients.Biomarkers and endosalpingiosis in the ovarian and tubal microenvironment of women at high-risk for pelvic serous carcinoma.Molecular origin of the binding of WWOX tumor suppressor to ErbB4 receptor tyrosine kinase.Potential of ErbB4 antibodies for cancer therapy.WWOX gene and gene product: tumor suppression through specific protein interactions.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Role of ErbB4 in breast cancer.
@en
Role of ErbB4 in breast cancer.
@nl
type
label
Role of ErbB4 in breast cancer.
@en
Role of ErbB4 in breast cancer.
@nl
prefLabel
Role of ErbB4 in breast cancer.
@en
Role of ErbB4 in breast cancer.
@nl
P2093
P1476
Role of ErbB4 in breast cancer.
@en
P2093
Henri Sara
Kristiina Iljin
Maria Sundvall
Sami Kilpinen
P2888
P304
P356
10.1007/S10911-008-9079-3
P577
2008-05-03T00:00:00Z