Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.
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A mitochondrial enzyme degrades carotenoids and protects against oxidative stressMammalian metabolism of β-carotene: gaps in knowledgeBeta-carotene reduces body adiposity of mice via BCMO1Genetic Variations Involved in Vitamin E StatusA genetic dissection of intestinal fat-soluble vitamin and carotenoid absorptionAddressing the inter-individual variation in response to consumption of plant food bioactives: Towards a better understanding of their role in healthy aging and cardiometabolic risk reduction.Biochemical evidence for the tyrosine involvement in cationic intermediate stabilization in mouse beta-carotene 15, 15'-monooxygenase.A nonsense mutation in the beta-carotene oxygenase 2 (BCO2) gene is tightly associated with accumulation of carotenoids in adipose tissue in sheep (Ovis aries).Prioritizing GWAS results: A review of statistical methods and recommendations for their application.ISX is a retinoic acid-sensitive gatekeeper that controls intestinal beta,beta-carotene absorption and vitamin A production.Significant correlations of dermal total carotenoids and dermal lycopene with their respective plasma levels in healthy adults.Association between optimism and serum antioxidants in the midlife in the United States study.Systems Epidemiology: A New Direction in Nutrition and Metabolic Disease ResearchUse of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health.Single nucleotide polymorphisms upstream from the β-carotene 15,15'-monoxygenase gene influence provitamin A conversion efficiency in female volunteers.Racial differences in correlations between reported dietary intakes of carotenoids and their concentration biomarkers.Low-serum carotenoid concentrations and carotenoid interactions predict mortality in US adults: the Third National Health and Nutrition Examination SurveyGenetic variation predicts serum lycopene concentrations in a multiethnic population of postmenopausal women.Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants.Mammalian carotenoid-oxygenases: key players for carotenoid function and homeostasisGenome-wide association study identifies common variants associated with circulating vitamin E levels.Serum carotenoid concentrations predict lung function evolution in young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) studyGenome-wide association study of circulating retinol levels.The Effect of BCMO1 Gene Variants on Macular Pigment Optical Density in Young Healthy Caucasians.Premenopausal plasma carotenoids, fluorescent oxidation products, and subsequent breast cancer risk in the nurses' health studies.Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in menPlasma and tissue concentrations of α-tocopherol and δ-tocopherol following high dose dietary supplementation in mice.BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway.Common SNP rs6564851 in the BCO1 Gene Affects the Circulating Levels of β-Carotene and the Daily Intake of Carotenoids in Healthy Japanese WomenThe putative role of lutein and zeaxanthin as protective agents against age-related macular degeneration: promise of molecular genetics for guiding mechanistic and translational research in the field.Provitamin A metabolism and functions in mammalian biology.β-Carotene 15,15'-monooxygenase 1 single nucleotide polymorphisms in relation to plasma carotenoid and retinol concentrations in women of European descent.The association between a biomarker score for fruit and vegetable intake and incident type 2 diabetes: the EPIC-Norfolk study.Mechanisms involved in the intestinal absorption of dietary vitamin A and provitamin A carotenoids.A Common Variant in the SETD7 Gene Predicts Serum Lycopene Concentrations.Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX.Genetic determinants of macular pigments in women of the Carotenoids in Age-Related Eye Disease StudyPlasma carotenoid- and retinol-weighted multi-SNP scores and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.Single nucleotide polymorphisms in CETP, SLC46A1, SLC19A1, CD36, BCMO1, APOA5, and ABCA1 are significant predictors of plasma HDL in healthy adultsAbsorption, metabolism, and functions of β-cryptoxanthin
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Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 29 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Common variation in the beta-c ...... genome-wide association study.
@en
Common variation in the beta-c ...... genome-wide association study.
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type
label
Common variation in the beta-c ...... genome-wide association study.
@en
Common variation in the beta-c ...... genome-wide association study.
@nl
prefLabel
Common variation in the beta-c ...... genome-wide association study.
@en
Common variation in the beta-c ...... genome-wide association study.
@nl
P2093
P2860
P50
P1476
Common variation in the beta-c ...... genome-wide association study.
@en
P2093
Amy Matteini
Anna-Maria Corsi
Christie Cluett
Jack Guralnik
Jeremy Walston
John R B Perry
Linda P Fried
Toshiko Tanaka
P2860
P304
P356
10.1016/J.AJHG.2008.12.019
P407
P50
P577
2009-01-29T00:00:00Z