Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4.
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Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathyAngiopoietin-like 4 promotes angiogenesis in the tendon and is increased in cyclically loaded tendon fibroblastsThe severity of retinal pathology in homozygous Crb1rd8/rd8 mice is dependent on additional genetic factors.Promoting vascular repair in the retina: can stem/progenitor cells help?Human adipose tissue expansion in pregnancy is impaired in gestational diabetes mellitus.Progression of Diabetic Capillary Occlusion: A Model.Expression Pattern of HIF-1α and VEGF Supports Circumferential Application of Scatter Laser for Proliferative Sickle Retinopathy.Transplantation of lineage-negative stem cells in pterygopalatine artery ligation induced retinal ischemia-reperfusion injury in mice.Pathogenic role of lncRNA-MALAT1 in endothelial cell dysfunction in diabetes mellitusSOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growthPreventive Effects of the Chinese Herbal Medicine Prescription Tangkuei Decoction for Frigid Extremities on Sciatic Neuropathy in Streptozotocin-Induced Diabetic Rats.Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma.In Vivo Imaging of Retinal Hypoxia in a Model of Oxygen-Induced RetinopathyQuantitative analyses of retinal vascular area and density after different methods to reduce VEGF in a rat model of retinopathy of prematurity.Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway.Digoxin-induced retinal degeneration depends on rhodopsin.Sumoylation of hypoxia inducible factor-1α and its significance in cancer.Hypoxia and Dark Adaptation in Diabetic Retinopathy: Interactions, Consequences, and Therapy.Retinal fibrosis in diabetic retinopathyIdentification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy.Differential hypoxic response of human choroidal and retinal endothelial cells proposes tissue heterogeneity of ocular angiogenesis.Anti-angiogenic Therapy for Retinal Disease.New Developments in the Classification, Pathogenesis, Risk Factors, Natural History, and Treatment of Branch Retinal Vein OcclusionSystems biology of oxygen homeostasis.Expression of the angiogenic mediator, angiopoietin-like 4, in the eyes of patients with proliferative sickle retinopathy.TGF-β2-induced ANGPTL4 expression promotes tumor progression and osteoclast differentiation in giant cell tumor of bone.Hypoxia-Inducible Factor-Dependent Expression of Angiopoietin-Like 4 by Conjunctival Epithelial Cells Promotes the Angiogenic Phenotype of PterygiaLack of Evidence for Vasoactive and Inflammatory Mediators in the Promotion of Macular Edema Associated with Epiretinal Membranes.Cancer cells remodel themselves and vasculature to overcome the endothelial barrier.A hypoxia-responsive glial cell-specific gene therapy vector for targeting retinal neovascularization.Angiopoietin-like protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP.Role of interleukin-1β in hypoxia-induced depression of glutamate uptake in retinal Müller cells.Glaucoma, Stem Cells, and Gene Therapy: Where Are We Now?Plasma levels of hypoxia-regulated factors in patients with age-related macular degeneration.Expression of angiopoietin-like protein 8 correlates with VEGF in patients with proliferative diabetic retinopathy.The ROCK pathway inhibitor Y-27632 mitigates hypoxia and oxidative stress-induced injury to retinal Müller cells.A review of the multifunctionality of angiopoietin-like 4 in eye diseaseThe unfolded protein response signaling and retinal Müller cell metabolism
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P2860
Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 19 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Hypoxic retinal Muller cells p ...... lation of angiopoietin-like 4.
@en
Hypoxic retinal Muller cells p ...... lation of angiopoietin-like 4.
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type
label
Hypoxic retinal Muller cells p ...... lation of angiopoietin-like 4.
@en
Hypoxic retinal Muller cells p ...... lation of angiopoietin-like 4.
@nl
prefLabel
Hypoxic retinal Muller cells p ...... lation of angiopoietin-like 4.
@en
Hypoxic retinal Muller cells p ...... lation of angiopoietin-like 4.
@nl
P2093
P2860
P356
P1476
Hypoxic retinal Muller cells p ...... lation of angiopoietin-like 4.
@en
P2093
Akrit Sodhi
Derek S Welsbie
Elia J Duh
Fabiana Kashiwabuchi
Gerard Lutty
Imran Bhutto
James T Handa
Mahaa Umapathi
Murilo Rodrigues
P2860
P304
P356
10.1073/PNAS.1217091110
P407
P577
2013-08-19T00:00:00Z