Aging impairs electrical conduction along endothelium of resistance arteries through enhanced Ca2+-activated K+ channel activation.
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Oxidation of K(+) Channels in Aging and NeurodegenerationRegulation of increased blood flow (hyperemia) to muscles during exercise: a hierarchy of competing physiological needsIntegration and Modulation of Intercellular Signaling Underlying Blood Flow ControlFunctional sympatholysis and sympathetic escape in a theoretical model for blood flow regulation.Aging increases capacitance and spontaneous transient outward current amplitude of smooth muscle cells from murine superior epigastric arteries.Age-related impairment of conducted dilation in human coronary arteriolesAging alters reactivity of microvascular resistance networks in mouse gluteus maximus muscle.Upregulation of SK3 and IK1 channels contributes to the enhanced endothelial calcium signaling and the preserved coronary relaxation in obese Zucker rats.Making microvascular networks work: angiogenesis, remodeling, and pruning.Small conductance calcium-activated potassium current is important in transmural repolarization of failing human ventricles.Developmental conditioning of endothelium-derived hyperpolarizing factor-mediated vasorelaxationAdvanced age decreases local calcium signaling in endothelium of mouse mesenteric arteries in vivo.KCa 3.1 upregulation preserves endothelium-dependent vasorelaxation during aging and oxidative stressCalcium and electrical signaling in arterial endothelial tubes: New insights into cellular physiology and cardiovascular function.Advanced age protects microvascular endothelium from aberrant Ca(2+) influx and cell death induced by hydrogen peroxide.Impact of Aging on Calcium Signaling and Membrane Potential in Endothelium of Resistance Arteries: A Role for Mitochondria.EPA:DHA 6:1 prevents angiotensin II-induced hypertension and endothelial dysfunction in rats: role of NADPH oxidase- and COX-derived oxidative stress.The vascular endothelium: A regulator of arterial tone and interface for the immune system.Rapid versus slow ascending vasodilatation: intercellular conduction versus flow-mediated signalling with tetanic versus rhythmic muscle contractions.Hyperglycaemia disrupts conducted vasodilation in the resistance vasculature of db/db mice.Differential α-adrenergic modulation of rapid onset vasodilatation along resistance networks of skeletal muscle in old versus young mice.Pharmacologic targeting of endothelial Ca2+-activated K+ channels: A strategy to improve cardiovascular function.Depressed perivascular sensory innervation of mouse mesenteric arteries with advanced age.Membrane potential governs calcium influx into microvascular endothelium: integral role for muscarinic receptor activation.Voltage-gated potassium+ channel expression in coronary artery smooth muscle cells of SHR and WKY.Electrical dynamics of isolated cerebral and skeletal muscle endothelial tubes: Differential roles of G-protein-coupled receptors and K+ channels.
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Aging impairs electrical conduction along endothelium of resistance arteries through enhanced Ca2+-activated K+ channel activation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 30 May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Aging impairs electrical condu ...... tivated K+ channel activation.
@en
Aging impairs electrical condu ...... tivated K+ channel activation.
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type
label
Aging impairs electrical condu ...... tivated K+ channel activation.
@en
Aging impairs electrical condu ...... tivated K+ channel activation.
@nl
prefLabel
Aging impairs electrical condu ...... tivated K+ channel activation.
@en
Aging impairs electrical condu ...... tivated K+ channel activation.
@nl
P2093
P2860
P1476
Aging impairs electrical condu ...... tivated K+ channel activation.
@en
P2093
Erik J Behringer
Erika B Westcott
Matthew J Socha
Rebecca L Shaw
Steven S Segal
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P304
P356
10.1161/ATVBAHA.113.301514
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P577
2013-05-30T00:00:00Z