Autophagy mediated by arginine depletion activation of the nutrient sensor GCN2 contributes to interferon-γ-induced malignant transformation of primary bovine mammary epithelial cells.
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Diet-driven interferon-γ enhances malignant transformation of primary bovine mammary epithelial cells through nutrient sensor GCN2-activated autophagy.Aberrant regulation of autophagy in mammalian diseases.Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy is dependent on the HMOX1 (heme oxygenase 1)-mediated increase in the intracellular calcium levels and modulation of PPP3/calcineurin-TFEB (transcription factor EB) axis.GCN2 controls the cellular checkpoint: potential target for regulating inflammation.
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Autophagy mediated by arginine depletion activation of the nutrient sensor GCN2 contributes to interferon-γ-induced malignant transformation of primary bovine mammary epithelial cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 25 January 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Autophagy mediated by arginine ...... vine mammary epithelial cells.
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Autophagy mediated by arginine ...... vine mammary epithelial cells.
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type
label
Autophagy mediated by arginine ...... vine mammary epithelial cells.
@en
Autophagy mediated by arginine ...... vine mammary epithelial cells.
@nl
prefLabel
Autophagy mediated by arginine ...... vine mammary epithelial cells.
@en
Autophagy mediated by arginine ...... vine mammary epithelial cells.
@nl
P2093
P2860
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P1476
Autophagy mediated by arginine ...... vine mammary epithelial cells.
@en
P2093
P2860
P2888
P356
10.1038/CDDISCOVERY.2015.65
P577
2016-01-25T00:00:00Z