Spontaneous malignant transformation of melanocytes explanted from Wf/Wf mice with a Kit kinase-domain mutation. - Wikidata - wikimedia - TriplyDB

Spontaneous malignant transformation of melanocytes explanted from Wf/Wf mice with a Kit kinase-domain mutation.

Spontaneous malignant transformation of melanocytes explanted from Wf/Wf mice with a Kit kinase-domain mutation.

http://www.wikidata.org/entity/Q37165743

about

Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis Immunohistochemical determination of HER-2/neu overexpression in malignant melanoma reveals no prognostic value, while c-Kit (CD117) overexpression exhibits potential therapeutic implications NUAK2 Amplification Coupled with PTEN Deficiency Promotes Melanoma Development via CDK Activation.Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression.Tissue inducible Lifeact expression allows visualization of actin dynamics in vivo and ex vivo Ror2 enhances polarity and directional migration of primordial germ cells.Driver mutations in melanoma: lessons learned from bench-to-bedside studies Specific analysis of KIT and PDGFR-alpha expression and mutational status in Merkel cell carcinoma.The molecular basis of human piebaldism.Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development.Activated mutant NRas(Q61K) drives aberrant melanocyte signaling, survival, and invasiveness via a Rac1-dependent mechanism.Phenotypic reversions at the W/Kit locus mediated by mitotic recombination in mice.Phosphorylation of BRN2 modulates its interaction with the Pax3 promoter to control melanocyte migration and proliferation.recessive spotting: a linked locus that interacts with W/Kit but is not allelic.Genetic variation at KIT locus may predispose to melanoma.Identification of a novel cDNA clone encoding protein tyrosine kinase in murine skin.

P2860

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P2860

Spontaneous malignant transformation of melanocytes explanted from Wf/Wf mice with a Kit kinase-domain mutation.

http://www.wikidata.org/entity/Q37165743

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on August 1992

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Spontaneous malignant transfor ...... a Kit kinase-domain mutation.

@en

Spontaneous malignant transfor ...... a Kit kinase-domain mutation.

@nl

type

label

Spontaneous malignant transfor ...... a Kit kinase-domain mutation.

@en

Spontaneous malignant transfor ...... a Kit kinase-domain mutation.

@nl

prefLabel

Spontaneous malignant transfor ...... a Kit kinase-domain mutation.

@en

Spontaneous malignant transfor ...... a Kit kinase-domain mutation.

@nl

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P356

PNAS.89.16.7816

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Spontaneous malignant transfor ...... a Kit kinase-domain mutation.

@en

P2093

B Mintz

http://www.w3.org/2001/XMLSchema#string

L Larue

http://www.w3.org/2001/XMLSchema#string

N Dougherty

http://www.w3.org/2001/XMLSchema#string

S Porter

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P2860

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand

Gene control of mammalian pigmentary differentiation. I. Clonal origin of melanocytes

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.

Analysis of pleiotropism at the dominant white-spotting (W) locus of the house mouse: a description of ten new W alleles

Clonal basis of mammalian differentiation.

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus.

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

P304

7816-7820

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scholarly article

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10.1073/PNAS.89.16.7816

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16

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89

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21775881

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1380168

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49802

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