Regulation and functions of sphingosine kinases in the brain
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Alcohol, insulin resistance and the liver-brain axisTherapeutic targets of brain insulin resistance in sporadic Alzheimer's diseaseSphingosine kinase 1 deficiency exacerbates LPS-induced neuroinflammationBrain insulin resistance and deficiency as therapeutic targets in Alzheimer's diseaseSphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNSCeramide-mediated insulin resistance and impairment of cognitive-motor functionsNeurons and oligodendrocytes recycle sphingosine 1-phosphate to ceramide: significance for apoptosis and multiple sclerosisExpression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration.Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes.Sphingosine kinase 1 in cancer.Cellular localization of sphingosine-1-phosphate receptor 1 expression in the human central nervous systemMetabolic derangements mediate cognitive impairment and Alzheimer's disease: role of peripheral insulin-resistance diseasesExpression of sphingosine kinase 1 in amoeboid microglial cells in the corpus callosum of postnatal rats.Recruitment of sphingosine kinase to presynaptic terminals by a conserved muscarinic signaling pathway promotes neurotransmitter releaseMechanisms of ceramide-mediated neurodegeneration.Brain metabolic dysfunction at the core of Alzheimer's disease.Triangulated mal-signaling in Alzheimer's disease: roles of neurotoxic ceramides, ER stress, and insulin resistance reviewedIntracranial Injection of Dengue Virus Induces Interferon Stimulated Genes and CD8+ T Cell Infiltration by Sphingosine Kinase 1 Independent PathwaysRapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition.Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitroLysophospholipid receptors in vertebrate development, physiology, and pathology.Endocytosis and intracellular processing of BODIPY-sphingomyelin by murine CATH.a neurons.The liver-brain axis of alcohol-mediated neurodegeneration: role of toxic lipids.Hypoxic preconditioning-induced cerebral ischemic tolerance: role of microvascular sphingosine kinase 2.Export and functions of sphingosine-1-phosphate.Insulin resistance and neurodegeneration: roles of obesity, type 2 diabetes mellitus and non-alcoholic steatohepatitis.Exploring neuroinflammation as a potential avenue to improve the clinical efficacy of opioids.Sphingolipids: key regulators of apoptosis and pivotal players in cancer drug resistanceSepsis-Associated Encephalopathy: The Blood-Brain Barrier and the Sphingolipid Rheostat.Gilenya (FTY720) inhibits acid sphingomyelinase by a mechanism similar to tricyclic antidepressants.Sphingosine kinase 2 mediates cerebral preconditioning and protects the mouse brain against ischemic injury.Sphingosine kinase 2-deficiency mediated changes in spinal pain processing.Crosstalk between TLR2 and Sphk1 in microglia in the cerebral ischemia/reperfusion-induced inflammatory response.TUDCA: An Agonist of the Bile Acid Receptor GPBAR1/TGR5 With Anti-Inflammatory Effects in Microglial Cells.Sphingolipids role in the regulation of inflammatory response: From leukocyte biology to bacterial infection.Effects of small interfering RNA targeting sphingosine kinase-1 gene on the animal model of Alzheimer's disease.Deconvolution of Human Brain Cell Type Transcriptomes Unraveled Microglia-Specific Potential Biomarkers.Conjugated Bile Acids Promote Invasive Growth of Esophageal Adenocarcinoma Cells and Cancer Stem Cell Expansion via Sphingosine 1-Phosphate Receptor 2-Mediated Yes-Associated Protein Activation
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Regulation and functions of sphingosine kinases in the brain
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 29 April 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Regulation and functions of sphingosine kinases in the brain
@en
Regulation and functions of sphingosine kinases in the brain.
@nl
type
label
Regulation and functions of sphingosine kinases in the brain
@en
Regulation and functions of sphingosine kinases in the brain.
@nl
prefLabel
Regulation and functions of sphingosine kinases in the brain
@en
Regulation and functions of sphingosine kinases in the brain.
@nl
P2093
P2860
P1476
Regulation and functions of sphingosine kinases in the brain
@en
P2093
Lauren Bryan
Sheldon Milstien
Tomasz Kordula
P2860
P304
P356
10.1016/J.BBALIP.2008.04.008
P407
P577
2008-04-29T00:00:00Z