Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p.
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Physiologically Shrinking the Solution Space of a Saccharomyces cerevisiae Genome-Scale Model Suggests the Role of the Metabolic Network in Shaping Gene Expression NoiseParts plus pipes: synthetic biology approaches to metabolic engineeringSampling the solution space in genome-scale metabolic networks reveals transcriptional regulation in key enzymesShrinking the metabolic solution space using experimental datasetsModeling phenotypic metabolic adaptations of Mycobacterium tuberculosis H37Rv under hypoxiaSystematic evaluation of methods for integration of transcriptomic data into constraint-based models of metabolismComputational analysis of reciprocal association of metabolism and epigenetics in the budding yeast: a genome-scale metabolic model (GSMM) approachBiofilm Formation Mechanisms of Pseudomonas aeruginosa Predicted via Genome-Scale Kinetic Models of Bacterial MetabolismIntegration of expression data in genome-scale metabolic network reconstructions.Metabolic network analysis of Pseudomonas aeruginosa during chronic cystic fibrosis lung infectionFunctional integration of a metabolic network model and expression data without arbitrary thresholding.Mapping global effects of the anti-sigma factor MucA in Pseudomonas fluorescens SBW25 through genome-scale metabolic modelingIntegration of transcription and flux data reveals molecular paths associated with differences in oxygen-dependent phenotypes of Saccharomyces cerevisiae.Methods for integration of transcriptomic data in genome-scale metabolic models.Investigation on metabolism of cisplatin resistant ovarian cancer using a genome scale metabolic model and microarray dataA Method to Constrain Genome-Scale Models with 13C Labeling Data.Transcriptomic and metabolomic data integration.OM-FBA: Integrate Transcriptomics Data with Flux Balance Analysis to Decipher the Cell MetabolismOptORF: Optimal metabolic and regulatory perturbations for metabolic engineering of microbial strains.Systems-biology dissection of eukaryotic cell growthFlux-Enabled Exploration of the Role of Sip1 in Galactose Yeast MetabolismAn automated phenotype-driven approach (GeneForce) for refining metabolic and regulatory models.Bridging the gap between gene expression and metabolic phenotype via kinetic modelsContribution of network connectivity in determining the relationship between gene expression and metabolite concentration changes.Source and regulation of flux variability in Escherichia coli.Metabolome searcher: a high throughput tool for metabolite identification and metabolic pathway mapping directly from mass spectrometry and using genome restrictionThe effect of short-term hypoxic exposure on metabolic gene expression.Context-Specific Metabolic Model Extraction Based on Regularized Least Squares Optimization.Integrated in silico Analyses of Regulatory and Metabolic Networks of Synechococcus sp. PCC 7002 Reveal Relationships between Gene Centrality and EssentialityModular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine.Functional genomics tools applied to plant metabolism: a survey on plant respiration, its connections and the annotation of complex gene functions.Complex systems: from chemistry to systems biology.Mapping condition-dependent regulation of lipid metabolism in Saccharomyces cerevisiae13C Metabolic Flux Analysis for Systematic Metabolic Engineering of S. cerevisiae for Overproduction of Fatty Acids.Topological augmentation to infer hidden processes in biological systems.Eukaryotic and archaeal translation initiation factor 2: a heterotrimeric tRNA carrier.Synthetic biology: tools to design, build, and optimize cellular processes.Systems metabolic engineering: genome-scale models and beyond.Toward design-based engineering of industrial microbes.Metabolomics in systems microbiology
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P2860
Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 03 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Linking high-resolution metabo ...... by the global regulator Gcn4p.
@en
Linking high-resolution metabo ...... by the global regulator Gcn4p.
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type
label
Linking high-resolution metabo ...... by the global regulator Gcn4p.
@en
Linking high-resolution metabo ...... by the global regulator Gcn4p.
@nl
prefLabel
Linking high-resolution metabo ...... by the global regulator Gcn4p.
@en
Linking high-resolution metabo ...... by the global regulator Gcn4p.
@nl
P2093
P2860
P50
P356
P1476
Linking high-resolution metabo ...... by the global regulator Gcn4p.
@en
P2093
Alan G Hinnebusch
Gregory Stephanopoulos
Joel F Moxley
Michael C Jewett
Robert T Wheeler
Trey Ideker
P2860
P304
P356
10.1073/PNAS.0811091106
P407
P577
2009-04-03T00:00:00Z