Xanthine oxidoreductase depletion induces renal interstitial fibrosis through aberrant lipid and purine accumulation in renal tubules.
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Xanthine Oxidoreductase-Derived Reactive Species: Physiological and Pathological EffectsXanthine oxidoreductase in cancer: more than a differentiation markerRole of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic SteatohepatitisUntargeted plasma metabolite profiling reveals the broad systemic consequences of xanthine oxidoreductase inactivation in miceA mouse model of early-onset renal failure due to a xanthine dehydrogenase nonsense mutationCadmium exposure and its association with serum uric acid and hyperuricemia.Renal lipid metabolism and lipotoxicity.Chemistry meets biology in colitis-associated carcinogenesisQuercetin Protects against Cadmium-Induced Renal Uric Acid Transport System Alteration and Lipid Metabolism Disorder in Rats.The renal phenotype of allopurinol-treated HPRT-deficient mouse.Uric acid as a target of therapy in CKD.Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation.Uric acid secretion from adipose tissue and its increase in obesityXanthine oxidoreductase: a journey from purine metabolism to cardiovascular excitation-contraction coupling.Molecular biology of atherosclerosis.Xanthine dehydrogenase downregulation promotes TGFβ signaling and cancer stem cell-related gene expression in hepatocellular carcinoma.Effects of the AT(1) receptor blocker losartan and the calcium channel blocker benidipine on the accumulation of lipids in the kidney of a rat model of metabolic syndrome.Xanthine oxidoreductase mediates membrane docking of milk-fat droplets but is not essential for apocrine lipid secretion.Mouse model for molybdenum cofactor deficiency type B recapitulates the phenotype observed in molybdenum cofactor deficient patients.
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P2860
Xanthine oxidoreductase depletion induces renal interstitial fibrosis through aberrant lipid and purine accumulation in renal tubules.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Xanthine oxidoreductase deplet ...... accumulation in renal tubules.
@en
Xanthine oxidoreductase deplet ...... accumulation in renal tubules.
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type
label
Xanthine oxidoreductase deplet ...... accumulation in renal tubules.
@en
Xanthine oxidoreductase deplet ...... accumulation in renal tubules.
@nl
prefLabel
Xanthine oxidoreductase deplet ...... accumulation in renal tubules.
@en
Xanthine oxidoreductase deplet ...... accumulation in renal tubules.
@nl
P2093
P2860
P1433
P1476
Xanthine oxidoreductase deplet ...... accumulation in renal tubules.
@en
P2093
Hideko Noguchi
Ilsa I Rovira
Kanae Sakagami
Kazuhiko Tsuruya
Kiyoshi Matsumura
Koji Fujii
Mitsuo Iida
Toren Finkel
Toshio Ohtsubo
P2860
P304
P356
10.1161/HYPERTENSIONAHA.109.135152
P407
P577
2009-08-10T00:00:00Z