Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice.
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NHE8 plays important roles in gastric mucosal protectionPhysiology of na+/h+ exchangers in the male reproductive tract: relevance for male fertilityProximal tubular NHEs: sodium, protons and calcium?Mechanisms Underlying Dysregulation of Electrolyte Absorption in Inflammatory Bowel Disease-Associated DiarrheaIntestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans.Loss of NHE8 expression impairs ocular surface function in miceDisruption of NHE8 expression impairs Leydig cell function in the testes.Congenital chloride-losing diarrhea in a Mexican child with the novel homozygous SLC26A3 mutation G393W.Mouse slc9a8 mutants exhibit retinal defects due to retinal pigmented epithelium dysfunction.Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity.Loss of NHE8 expression impairs intestinal mucosal integrity.Intestinal NHE8 is highly expressed in goblet cells and its expression is subject to TNF-α regulationNHE8 plays an important role in mucosal protection via its effect on bacterial adhesionPathophysiology of Intestinal Na+/H+ exchange.Traditional and emerging roles for the SLC9 Na+/H+ exchangers.Epithelial transport in inflammatory bowel diseases.Role of epithelial ion transports in inflammatory bowel disease.Somatostatin regulates NHE8 protein expression via the ERK1/2 MAPK pathway in DSS-induced colitis mice.Loss of the Na+/H+ exchanger NHE8 causes male infertility in mice by disrupting acrosome formation.Bile acids inhibit Na⁺/H⁺ exchanger and Cl⁻/HCO₃⁻ exchanger activities via cellular energy breakdown and Ca²⁺ overload in human colonic crypts
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Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 May 2012
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice.
@en
Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice.
@nl
type
label
Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice.
@en
Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice.
@nl
prefLabel
Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice.
@en
Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice.
@nl
P2093
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P356
P1476
Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice.
@en
P2093
Chunhui Wang
Fayez K Ghishan
Huacong Chen
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P304
P356
10.1152/AJPGI.00146.2012
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2012-05-10T00:00:00Z