Inducible activation of Cre recombinase in adult mice causes gastric epithelial atrophy, metaplasia, and regenerative changes in the absence of "floxed" alleles.
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Stomach development, stem cells and diseaseMutants of Cre recombinase with improved accuracyRapid Knockout and Reporter Mouse Line Generation and Breeding Colony Establishment Using EUCOMM Conditional-Ready Embryonic Stem Cells: A Case StudyTranscriptome signatures in Helicobacter pylori-infected mucosa identifies acidic mammalian chitinase loss as a corpus atrophy markerComparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice.The transcription factor MIST1 is a novel human gastric chief cell marker whose expression is lost in metaplasia, dysplasia, and carcinoma.Gastric epithelial stem cellsCre-mediated recombination can induce apoptosis in vivo by activating the p53 DNA damage-induced pathwayBladder function in mice with inducible smooth muscle-specific deletion of the manganese superoxide dismutase gene.Prolonged Cre expression driven by the α-myosin heavy chain promoter can be cardiotoxic.The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturationNew inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism.Beyond knockouts: cre resources for conditional mutagenesis.Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury.Tamoxifen induces rapid, reversible atrophy, and metaplasia in mouse stomach.Stomach Organ and Cell Lineage Differentiation: from Embryogenesis to Adult Homeostasis.Schwann Cells in Neuromuscular Junction Formation and MaintenanceModeling Murine Gastric Metaplasia Through Tamoxifen-Induced Acute Parietal Cell Loss.Targeted mutagenesis tools for modelling psychiatric disorders.Cre recombinase induces DNA damage and tetraploidy in the absence of loxP sites.Hepatocyte nuclear factor 4α is required for cell differentiation and homeostasis in the adult mouse gastric epithelium.Unintended targeting of Dmp1-Cre reveals a critical role for Bmpr1a signaling in the gastrointestinal mesenchyme of adult mice.Adult gastric stem cells and their niches.Regulation of Gastric Metaplasia, Dysplasia, and Neoplasia by Bone Morphogenetic Protein Signaling.XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulumAll-in-one construct for genome engineering using Cre-lox technology.Sonic Hedgehog contributes to gastric mucosal restitution after injury.
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P2860
Inducible activation of Cre recombinase in adult mice causes gastric epithelial atrophy, metaplasia, and regenerative changes in the absence of "floxed" alleles.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 22 April 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Inducible activation of Cre re ...... e absence of "floxed" alleles.
@en
Inducible activation of Cre re ...... e absence of "floxed" alleles.
@nl
type
label
Inducible activation of Cre re ...... e absence of "floxed" alleles.
@en
Inducible activation of Cre re ...... e absence of "floxed" alleles.
@nl
prefLabel
Inducible activation of Cre re ...... e absence of "floxed" alleles.
@en
Inducible activation of Cre re ...... e absence of "floxed" alleles.
@nl
P2093
P2860
P356
P1476
Inducible activation of Cre re ...... e absence of "floxed" alleles.
@en
P2093
Indira U Mysorekar
Jason C Mills
Won Jae Huh
P2860
P304
P356
10.1152/AJPGI.00021.2010
P577
2010-04-22T00:00:00Z