Protein kinase C in heart failure: a therapeutic target? - Wikidata - wikimedia - TriplyDB

Protein kinase C in heart failure: a therapeutic target?

Protein kinase C in heart failure: a therapeutic target?

http://www.wikidata.org/entity/Q37176180

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Regulation of CaMKII signaling in cardiovascular disease Gap junction modulation and its implications for heart function Alteration of energy substrates and ROS production in diabetic cardiomyopathy Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal Infection Protein kinase C mechanisms that contribute to cardiac remodelling Interplay between troponin T phosphorylation and O-N-acetylglucosaminylation in ischaemic heart failure Protein kinase C: poised to signal Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias HASF is a stem cell paracrine factor that activates PKC epsilon mediated cytoprotection Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes Protein quality control disruption by PKCβII in heart failure; rescue by the selective PKCβII inhibitor, βIIV5-3 Oxidative Stress-Induced Afterdepolarizations and Protein Kinase C Signaling Simultaneous loss of phospholipase Cδ1 and phospholipase Cδ3 causes cardiomyocyte apoptosis and cardiomyopathy.Excision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffness G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C.Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotection Ischemia/reperfusion-induced myosin light chain 1 phosphorylation increases its degradation by matrix metalloproteinase 2.Disruption of adenylyl cyclase type V does not rescue the phenotype of cardiac-specific overexpression of Galphaq protein-induced cardiomyopathy Rosuvastatin-attenuated heart failure in aged spontaneously hypertensive rats via PKCα/β2 signal pathway Post-ischemic activation of protein kinase C ε protects the hippocampus from cerebral ischemic injury via alterations in cerebral blood flow.Protein kinase Cθ is required for cardiomyocyte survival and cardiac remodeling.Gene expression, function and ischemia tolerance in male and female rat hearts after sub-toxic levels of angiotensin II.Phorbol ester and endothelin-1 alter functional expression of Na+/Ca2+ exchange, K+, and Ca2+ currents in cultured neonatal rat myocytes Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy.Differential regulation of diacylglycerol kinase isoform in human failing hearts βIIPKC and εPKC isozymes as potential pharmacological targets in cardiac hypertrophy and heart failure PKCβII inhibition attenuates myocardial infarction induced heart failure and is associated with a reduction of fibrosis and pro-inflammatory responses Coronary artery ligation and intramyocardial injection in a murine model of infarction.Protein kinase Cα as a heart failure therapeutic target Titin-actin interaction: PEVK-actin-based viscosity in a large animal Studies on the regio- and diastereo-selective epoxidation of daphnanes and tiglianes.Two protein kinase C isoforms, δ and ε, regulate energy homeostasis in mitochondria by transmitting opposing signals to the pyruvate dehydrogenase complex.Pharmacological inhibition of βIIPKC is cardioprotective in late-stage hypertrophy.Myosin cross-bridge dynamics in patients with hypertension and concentric left ventricular remodeling.Correlation of Lower Concentrations of Hydrogen Sulfide with Activation of Protein Kinase CβII in Uremic Accelerated Atherosclerosis Patients Mitochondrial membrane permeabilization and cell death during myocardial infarction: roles of calcium and reactive oxygen species.The role of the paracrine/autocrine mediator endothelin-1 in regulation of cardiac contractility and growth.In vitro effects of sodium nitroprusside and leptin on norepinephrine-induced vasoconstriction in human internal mammary artery.A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity.

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Protein kinase C in heart failure: a therapeutic target?

http://www.wikidata.org/entity/Q37176180

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 24 January 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Protein kinase C in heart failure: a therapeutic target?

@en

Protein kinase C in heart failure: a therapeutic target?

@nl

type

label

Protein kinase C in heart failure: a therapeutic target?

@en

Protein kinase C in heart failure: a therapeutic target?

@nl

prefLabel

Protein kinase C in heart failure: a therapeutic target?

@en

Protein kinase C in heart failure: a therapeutic target?

@nl

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Cardiovascular Research

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Protein kinase C in heart failure: a therapeutic target?

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Julio Cesar Batista Ferreira

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Lihan Sun

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Suresh Selvaraj Palaniyandi

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Creative Commons Attribution-NonCommercial

P2860

Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5

Cardiotrophic effects of protein kinase C epsilon: analysis by in vivo modulation of PKCepsilon translocation

Transgenic overexpression of constitutively active protein kinase C epsilon causes concentric cardiac hypertrophy

Activation of focal adhesion kinase by protein kinase C epsilon in neonatal rat ventricular myocytes

Identification of a functionally critical protein kinase C phosphorylation residue of cardiac troponin T

Tissue angiotensin II during progression or ventricular hypertrophy to heart failure in hypertensive rats; differential effects on PKC epsilon and PKC beta

Localization of protein kinase C isozymes in cardiac myocytes

Increased protein kinase C activity in myotrophin-induced myocyte growth

Pharmacological inhibition of epsilon-protein kinase C attenuates cardiac fibrosis and dysfunction in hypertension-induced heart failure

PKC alpha regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2)

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10.1093/CVR/CVP001

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Daria Mochly-Rosen

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2009-05-01T00:00:00Z

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