FGF9 monomer-dimer equilibrium regulates extracellular matrix affinity and tissue diffusion.
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Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitorsHeterozygous mutations of FREM1 are associated with an increased risk of isolated metopic craniosynostosis in humans and miceA Genetic-Pathophysiological Framework for CraniosynostosisFibroblast growth factor signaling in skeletal development and diseaseExtracellular distribution of diffusible growth factors controlled by heparan sulfate proteoglycans during mammalian embryogenesisExploring mechanisms of FGF signalling through the lens of structural biologyApplication of VEGFA and FGF-9 enhances angiogenesis, osteogenesis and bone remodeling in type 2 diabetic long bone regenerationTransport of fibroblast growth factor 2 in the pericellular matrix is controlled by the spatial distribution of its binding sites in heparan sulfateSelectivity in glycosaminoglycan binding dictates the distribution and diffusion of fibroblast growth factors in the pericellular matrix.Homodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular MatrixGenetic insights into the mechanisms of Fgf signalingMolecular mechanisms of fibroblast growth factor signaling in physiology and pathologyReduced BMP signaling results in hindlimb fusion with lethal pelvic/urogenital organ aplasia: a new mouse model of sirenomeliaThe pathologic effect of a novel neomorphic Fgf9(Y162C) allele is restricted to decreased vision and retarded lens growthExtending the family table: Insights from beyond vertebrates into the regulation of embryonic development by FGFsAnalysis of the FGF gene family provides insights into aquatic adaptation in cetaceansA novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal.Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis.Phenotype profile of a genetic mouse model for Muenke syndrome.Hand2 ensures an appropriate environment for cardiac fusion by limiting Fibronectin functionDimerization capacities of FGF2 purified with or without heparin-affinity chromatographyThe Fibroblast Growth Factor signaling pathwayExtracellular matrix-modulated Heartless signaling in Drosophila blood progenitors regulates their differentiation via a Ras/ETS/FOG pathway and target of rapamycin function.Multiple synostoses syndrome is due to a missense mutation in exon 2 of FGF9 gene.Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease.Fibroblast growth factor-9 enhances M2 macrophage differentiation and attenuates adverse cardiac remodeling in the infarcted diabetic heartRole of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models.Glycosaminoglycan-dependent restriction of FGF diffusion is necessary for lacrimal gland development.Fibroblast Growth Factor-9 Activates c-Kit Progenitor Cells and Enhances Angiogenesis in the Infarcted Diabetic Heart.Signaling integration in the rugae growth zone directs sequential SHH signaling center formation during the rostral outgrowth of the palate.Heparan sulfotransferases Hs6st1 and Hs2st keep Erk in check for mouse corpus callosum development.Secreted Wnt "inhibitors" are not just inhibitors: regulation of extracellular Wnt by secreted Frizzled-related proteins.Role of FGFs/FGFRs in skeletal development and bone regeneration.The role of vertebrate models in understanding craniosynostosis.Gene mutations associated with anomalies of human gonad formation.Mechanisms of FGF gradient formation during embryogenesis.Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization.A point mutation in Fgf9 impedes joint interzone formation leading to multiple synostoses syndrome.Signaling networks in joint development.Relationship between the localization of fibroblast growth factor 9 in prostate cancer cells and postoperative recurrence.
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P2860
FGF9 monomer-dimer equilibrium regulates extracellular matrix affinity and tissue diffusion.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 15 February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
FGF9 monomer-dimer equilibrium ...... affinity and tissue diffusion.
@en
FGF9 monomer-dimer equilibrium ...... affinity and tissue diffusion.
@nl
type
label
FGF9 monomer-dimer equilibrium ...... affinity and tissue diffusion.
@en
FGF9 monomer-dimer equilibrium ...... affinity and tissue diffusion.
@nl
prefLabel
FGF9 monomer-dimer equilibrium ...... affinity and tissue diffusion.
@en
FGF9 monomer-dimer equilibrium ...... affinity and tissue diffusion.
@nl
P2093
P2860
P50
P356
P1433
P1476
FGF9 monomer-dimer equilibrium ...... affinity and tissue diffusion.
@en
P2093
Akihiko Okawa
Hirotaka Murakami
Mikako Shirouzu
Noriaki Okimoto
Noriyuki Futatsugi
Ryogo Akasaka
Sachiko Iseki
Shuichi Hiraoka
Taka Nakahara
Yo-Ichi Shiraishi
P2860
P2888
P304
P356
10.1038/NG.316
P407
P577
2009-02-15T00:00:00Z