Enterovirus infection of human islets of Langerhans affects β-cell function resulting in disintegrated islets, decreased glucose stimulated insulin secretion and loss of Golgi structure

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Echovirus 6 Infects Human Exocrine and Endocrine Pancreatic Cells and Induces Pro-Inflammatory Innate Immune Response Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells

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Enterovirus infection of human islets of Langerhans affects β-cell function resulting in disintegrated islets, decreased glucose stimulated insulin secretion and loss of Golgi structure

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 10 August 2016

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vetenskaplig artikel

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Enterovirus infection of human ...... on and loss of Golgi structure

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Enterovirus infection of human ...... n and loss of Golgi structure.

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Enterovirus infection of human ...... on and loss of Golgi structure

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Enterovirus infection of human ...... n and loss of Golgi structure.

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Enterovirus infection of human ...... on and loss of Golgi structure

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Enterovirus infection of human ...... n and loss of Golgi structure.

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Enterovirus infection of human ...... on and loss of Golgi structure

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A Lukinius

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B N G Giepmans

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G Frisk

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J Kuipers

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J M Isaza-Correa

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M Hodik

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P2860

Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies

Mapping the cleavage site in protein synthesis initiation factor eIF-4 gamma of the 2A proteases from human Coxsackievirus and rhinovirus

Mechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis

Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways

Cholesterol accumulation increases insulin granule size and impairs membrane trafficking.

Enteroviruses harness the cellular endocytic machinery to remodel the host cell cholesterol landscape for effective viral replication.

5'-Terminal deletions occur in coxsackievirus B3 during replication in murine hearts and cardiac myocyte cultures and correlate with encapsidation of negative-strand viral RNA.

Molecular mechanisms of coxsackievirus persistence in chronic inflammatory myopathy: viral RNA persists through formation of a double-stranded complex without associated genomic mutations or evolution

Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.

Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study.

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scholarly article

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10.1136/BMJDRC-2015-000179

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Oskar Skog

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2016-08-10T00:00:00Z

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glucose

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Enterovirus infection of human islets of Langerhans affects β-cell function resulting in disintegrated islets, decreased glucose stimulated insulin secretion and loss of Golgi structure

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P2860

P2860

Enterovirus infection of human islets of Langerhans affects β-cell function resulting in disintegrated islets, decreased glucose stimulated insulin secretion and loss of Golgi structure

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P1433

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