Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation - Wikidata - wikimedia - TriplyDB

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation

http://www.wikidata.org/entity/Q37178589

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C9orf72's Interaction with Rab GTPases-Modulation of Membrane Traffic and Autophagy Distinct C9orf72-Associated Dipeptide Repeat Structures Correlate with Neuronal Toxicity.The Proline/Arginine Dipeptide from Hexanucleotide Repeat Expanded C9ORF72 Inhibits the Proteasome Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients.Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene.Extra-motor abnormalities in amyotrophic lateral sclerosis: another layer of heterogeneity.The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD.New developments in RAN translation: insights from multiple diseases.Control of mRNA Translation in ALS Proteinopathy RNA Misprocessing in C9orf72-Linked Neurodegeneration.Photocontrolled reversible self-assembly of dodecamer nitrilase.Failure to Deliver and Translate-New Insights into RNA Dysregulation in ALS.Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.Regulation of mRNA Translation in Neurons-A Matter of Life and Death.RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response.Dysregulated molecular pathways in amyotrophic lateral sclerosis-frontotemporal dementia spectrum disorder.EAAT2 and the Molecular Signature of Amyotrophic Lateral Sclerosis.CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity.TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.Characterization of membrane penetration and cytotoxicity of C9orf72-encoding arginine-rich dipeptides Localization of RNAi Machinery to Axonal Branch Points and Growth Cones Is Facilitated by Mitochondria and Is Disrupted in ALS

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P2860

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation

http://www.wikidata.org/entity/Q37178589

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 29 February 2016

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vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

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name

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation

@en

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation.

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type

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Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation

@en

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation.

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prefLabel

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation

@en

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation.

@nl

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Human Molecular Genetics

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Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation

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Alexander J Cammack

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Fumihiko Urano

http://www.w3.org/2001/XMLSchema#string

Jana Mahadevan

http://www.w3.org/2001/XMLSchema#string

Kohsuke Kanekura

http://www.w3.org/2001/XMLSchema#string

Masahiko Kuroda

http://www.w3.org/2001/XMLSchema#string

Matthew B Harms

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Takuya Yagi

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Timothy M Miller

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P2860

RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention

Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

Hsp70 chaperones: cellular functions and molecular mechanism

The PANTHER database of protein families, subfamilies, functions and pathways

FFAS03: a server for profile--profile sequence alignments

Emerging mechanisms of molecular pathology in ALS

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1803-1813

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scholarly article

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10.1093/HMG/DDW052

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9

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25

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2016-02-29T00:00:00Z

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26931465

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4986334

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