SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway.
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SIRT1 protects against apoptosis by promoting autophagy in degenerative human disc nucleus pulposus cells.Neuroprotective effects of resveratrol on damages of mouse cortical neurons induced by β-amyloid through activation of SIRT1/Akt1 pathway.SIRT1 alleviates senescence of degenerative human intervertebral disc cartilage endo-plate cells via the p53/p21 pathway.SDF‑1/CXCR4 axis induces apoptosis of human degenerative nucleus pulposus cells via the NF‑κB pathway.Resveratrol attenuated TNF-α-induced MMP-3 expression in human nucleus pulposus cells by activating autophagy via AMPK/SIRT1 signaling pathway.Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo.ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration.Molecular mechanisms of cell death in intervertebral disc degeneration (Review).The Natural Polyphenol Epigallocatechin Gallate Protects Intervertebral Disc Cells from Oxidative Stress.Regulation of HepG2 cell apoptosis by hepatitis C virus (HCV) core protein via the sirt1-p53-bax pathway.The PI3K/Akt pathway: a critical player in intervertebral disc degeneration.IL-1β induces apoptosis and autophagy via mitochondria pathway in human degenerative nucleus pulposus cellsSIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle.SIRT1 induces resistance to apoptosis in human granulosa cells by activating the ERK pathway and inhibiting NF-κB signaling with anti-inflammatory functions.Resveratrol protects against sodium nitroprusside induced nucleus pulposus cell apoptosis by scavenging ROS.SIRT1 expression is refractory to hypoxia and inflammatory cytokines in nucleus pulposus cells: Novel regulation by HIF-1α and NF-κB signaling.Aberrantly expressed messenger RNAs and long noncoding RNAs in degenerative nucleus pulposus cells co-cultured with adipose-derived mesenchymal stem cells
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P2860
SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 19 September 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
SIRT1 inhibits apoptosis of de ...... ugh activation of Akt pathway.
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SIRT1 inhibits apoptosis of de ...... ugh activation of Akt pathway.
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type
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SIRT1 inhibits apoptosis of de ...... ugh activation of Akt pathway.
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SIRT1 inhibits apoptosis of de ...... ugh activation of Akt pathway.
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SIRT1 inhibits apoptosis of de ...... ugh activation of Akt pathway.
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SIRT1 inhibits apoptosis of de ...... ugh activation of Akt pathway.
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P2093
P2860
P1433
P1476
SIRT1 inhibits apoptosis of de ...... ugh activation of Akt pathway.
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P2093
JieLiang Shen
XiaoJun Zhang
XiaoMing Zhong
ZhenMing Hu
P2860
P304
P356
10.1007/S11357-012-9474-Y
P577
2012-09-19T00:00:00Z