Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons - Wikidata - wikimedia - TriplyDB

Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons

Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons

http://www.wikidata.org/entity/Q37180671

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Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease The role of oxidative stress in Parkinson's disease Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's disease Is cognitive functioning impaired in methamphetamine users? A critical review How addictive drugs disrupt presynaptic dopamine neurotransmission Degeneration of Dopaminergic Neurons Due to Metabolic Alterations and Parkinson's Disease The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic Potential SLC18: Vesicular neurotransmitter transporters for monoamines and acetylcholine Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Calcium, bioenergetics, and neuronal vulnerability in Parkinson's disease Mitochondrial dysfunction and oxidative stress in Parkinson's disease Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits.DNA variants in CACNA1C modify Parkinson disease risk only when vitamin D level is deficient.Physiological characterisation of human iPS-derived dopaminergic neurons Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function Edaravone guards dopamine neurons in a rotenone model for Parkinson's disease A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles.Vesicular integrity in Parkinson's disease Glutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagy Dopamine and paraquat enhance α-synuclein-induced alterations in membrane conductance Pro-survival role for Parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau.The Drosophila vesicular monoamine transporter reduces pesticide-induced loss of dopaminergic neurons.Serotonergic dystrophy induced by excess serotonin.L-type calcium channel blockers and Parkinson disease in Denmark.Hyperexcitable substantia nigra dopamine neurons in PINK1- and HtrA2/Omi-deficient mice.Ionic currents influencing spontaneous firing and pacemaker frequency in dopamine neurons of the ventrolateral periaqueductal gray and dorsal raphe nucleus (vlPAG/DRN): A voltage-clamp and computational modelling study.Investigating bacterial sources of toxicity as an environmental contributor to dopaminergic neurodegeneration.Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models Alpha-synuclein overexpression increases dopamine toxicity in BE2-M17 cells A FRET sensor for non-invasive imaging of amyloid formation in vivo.MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration Dopamine transporter trafficking: rapid response on demand.Reduced vesicular storage of catecholamines causes progressive degeneration in the locus ceruleus.Distinct region-specific alpha-synuclein oligomers in A53T transgenic mice: implications for neurodegeneration.A tyrosine-based motif localizes a Drosophila vesicular transporter to synaptic vesicles in vivo.Post translational changes to α-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson's disease.CNB-001 a novel curcumin derivative, guards dopamine neurons in MPTP model of Parkinson's disease.High regulatability favors genetic selection in SLC18A2, a vesicular monoamine transporter essential for life.Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo

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Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons

http://www.wikidata.org/entity/Q37180671

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on April 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Interplay between cytosolic do ...... th of substantia nigra neurons

@en

Interplay between cytosolic do ...... h of substantia nigra neurons.

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type

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Interplay between cytosolic do ...... th of substantia nigra neurons

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Interplay between cytosolic do ...... h of substantia nigra neurons.

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prefLabel

Interplay between cytosolic do ...... th of substantia nigra neurons

@en

Interplay between cytosolic do ...... h of substantia nigra neurons.

@nl

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J.NEURON.2009.01.033

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Interplay between cytosolic do ...... th of substantia nigra neurons

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David E Krantz

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Ellen Kanter

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Eugene V Mosharov

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Kazuto Kobayashi

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Kester A Phillips

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Kristin E Larsen

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Krystal Wilson

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Robert H Edwards

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Yvonne Schmitz

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P2860

Catecholamine Metabolism: A Contemporary View with Implications for Physiology and Medicine

Intraneuronal dopamine-quinone synthesis: A review

Dopamine covalently modifies and functionally inactivates parkin

Temporally resolved catecholamine spikes correspond to single vesicle release from individual chromaffin cells

Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy

Mechanisms of neurotransmitter release by amphetamines: a review

Tyrosine hydroxylase phosphorylation: regulation and consequences

'Rejuvenation' protects neurons in mouse models of Parkinson's disease

Substantia nigra neuromelanin: structure, synthesis, and molecular behaviour

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

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10.1016/J.NEURON.2009.01.033

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substantia nigra

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2677560

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