Pharmacokinetic Bioequivalence of Two Inhaled Tiotropium Bromide Formulations in Healthy Volunteers

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Response to Sharma et al.: Long Pulmonary Residence Time and Plasma Half-Life of Tiotropium: Implications for Pharmacokinetic Bioequivalence Studies.Long Pulmonary Residence Time and Plasma Half-Life of Tiotropium: Implications for Pharmacokinetic Bioequivalence Studies.

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Pharmacokinetic Bioequivalence of Two Inhaled Tiotropium Bromide Formulations in Healthy Volunteers

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scientific article published on 28 July 2016

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Pharmacokinetic Bioequivalence ...... ulations in Healthy Volunteers

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Pharmacokinetic Bioequivalence ...... lations in Healthy Volunteers.

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Pharmacokinetic Bioequivalence ...... ulations in Healthy Volunteers

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Pharmacokinetic Bioequivalence ...... lations in Healthy Volunteers.

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Pharmacokinetic Bioequivalence ...... ulations in Healthy Volunteers

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Pharmacokinetic Bioequivalence ...... lations in Healthy Volunteers.

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Pharmacokinetic Bioequivalence ...... ulations in Healthy Volunteers

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Fumin Li

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Jaime Algorta

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Jingduan Chi

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Laura Andrade

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Marta Medina

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Sacha Arsova

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Valentin Kirkov

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Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design

Tiotropium Bromide in Chronic Obstructive Pulmonary Disease and Bronchial Asthma

Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society

Metered-dose inhalers, dry powder inhalers, and transitions.

Pharmacokinetics and pharmacodynamics of tiotropium solution and tiotropium powder in chronic obstructive pulmonary disease

Inhaler devices for the treatment of asthma and chronic obstructive airways disease (COPD)

Pharmacokinetics and systemic effects of inhaled fluticasone propionate in chronic obstructive pulmonary disease.

Factors guiding the choice of delivery device for inhaled corticosteroids in the long-term management of stable asthma and COPD: focus on budesonide.

Lung deposition patterns of directly labelled salbutamol in normal subjects and in patients with reversible airflow obstruction

The bioavailability and airway clearance of the steroid component of budesonide/formoterol and salmeterol/fluticasone after inhaled administration in patients with COPD and healthy subjects: a randomized controlled trial.

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scholarly article

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10.1007/S40261-016-0441-8

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2016-07-28T00:00:00Z

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27470430

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4987402

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Pharmacokinetic Bioequivalence of Two Inhaled Tiotropium Bromide Formulations in Healthy Volunteers

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Pharmacokinetic Bioequivalence of Two Inhaled Tiotropium Bromide Formulations in Healthy Volunteers

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P2860

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P356

P433

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P577

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P433

P478

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