Engineering transcription factors with novel DNA-binding specificity using comparative genomics
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Cellular hyperproliferation and cancer as evolutionary variablesAnalyzing protein structure and function using ancestral gene reconstructionProgramming cells: towards an automated 'Genetic Compiler'Automatic design of digital synthetic gene circuitsEnhancing crop resilience to combined abiotic and biotic stress through the dissection of physiological and molecular crosstalk.Comparative genomics and evolution of regulons of the LacI-family transcription factors.Local gene regulation details a recognition code within the LacI transcriptional factor family.Bayesian multiple-instance motif discovery with BAMBI: inference of recombinase and transcription factor binding sitesGntR Family of Bacterial Transcription Factors and Their DNA Binding Motifs: Structure, Positioning and Co-Evolution.Identification of Position-Specific Correlations between DNA-Binding Domains and Their Binding Sites. Application to the MerR Family of Transcription Factors.Contextualizing context for synthetic biology--identifying causes of failure of synthetic biological systems.Modular control of multiple pathways using engineered orthogonal T7 polymerases.Directed evolution: new parts and optimized functionSynthetic biology: tools to design, build, and optimize cellular processes.Evaluation of novel design strategies for developing zinc finger nucleases tools for treating human diseases.Combinatorial targeting of ribbon-helix-helix artificial transcription factors to chimeric recognition sites.Improved production of a heterologous amylase in Saccharomyces cerevisiae by inverse metabolic engineering.Gly184 of the Escherichia coli cAMP receptor protein provides optimal context for both DNA binding and RNA polymerase interaction.
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P2860
Engineering transcription factors with novel DNA-binding specificity using comparative genomics
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 05 March 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Engineering transcription fact ...... ity using comparative genomics
@en
Engineering transcription fact ...... ty using comparative genomics.
@nl
type
label
Engineering transcription fact ...... ity using comparative genomics
@en
Engineering transcription fact ...... ty using comparative genomics.
@nl
prefLabel
Engineering transcription fact ...... ity using comparative genomics
@en
Engineering transcription fact ...... ty using comparative genomics.
@nl
P2093
P2860
P356
P1476
Engineering transcription fact ...... ity using comparative genomics
@en
P2093
Christopher V Rao
Eric J Alm
Tasha A Desai
P2860
P304
P356
10.1093/NAR/GKP079
P407
P577
2009-03-05T00:00:00Z