Alterations of the medullary epithelial compartment in the Aire-deficient thymus: implications for programs of thymic epithelial differentiation
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The many faces of aire in central tolerancePost-Aire Maturation of Thymic Medullary Epithelial Cells Involves Selective Expression of Keratinocyte-Specific AutoantigensAire and T cell developmentTranscriptional regulation by AIRE: molecular mechanisms of central toleranceInduction of central tolerance by the factor Aire: molecular and epigenetic regulationThe Contribution of Chemokines and Migration to the Induction of Central Tolerance in the ThymusThymic epithelial cell development and differentiation: cellular and molecular regulationIdentification of novel thymic epithelial cell subsets whose differentiation is regulated by RANKL and Traf6Autoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytesMorphogenesis and maintenance of the 3D thymic medulla and prevention of nude skin phenotype require FoxN1 in pre- and post-natal K14 epitheliumDKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration.ADAM17 deletion in thymic epithelial cells alters aire expression without affecting T cell developmental progressionTranscriptional and histological analyses of the thymic developmental process in the fetal pigThree distinct subsets of thymic epithelial cells in rats and mice defined by novel antibodies.DNA methylation profile of Aire-deficient mouse medullary thymic epithelial cellsβ-catenin activation drives thymoma initiation and progression in miceRB inactivation in keratin 18 positive thymic epithelial cells promotes non-cell autonomous T cell hyperproliferation in genetically engineered mice.Premature thymic involution is independent of structural plasticity of the thymic stroma.IRF7-dependent IFN-β production in response to RANKL promotes medullary thymic epithelial cell development.Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases.The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor.Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression.Human APECED; a Sick Thymus Syndrome?Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells.Peripheral T cells in the thymus: have they just lost their way or do they do something?Learning to be tolerant: how T cells keep out of trouble.Thymic epithelial cell development and its dysfunction in human diseases.Contrasting models for the roles of Aire in the differentiation program of epithelial cells in the thymic medulla.Models of aire-dependent gene regulation for thymic negative selection.TNF receptor family signaling in the development and functions of medullary thymic epithelial cells.Thymic stromal cell subsets for T cell development.Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiationT-cell tolerance: central and peripheralTwenty Years of AIRE.Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism
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P2860
Alterations of the medullary epithelial compartment in the Aire-deficient thymus: implications for programs of thymic epithelial differentiation
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Alterations of the medullary e ...... mic epithelial differentiation
@en
Alterations of the medullary e ...... ic epithelial differentiation.
@nl
type
label
Alterations of the medullary e ...... mic epithelial differentiation
@en
Alterations of the medullary e ...... ic epithelial differentiation.
@nl
prefLabel
Alterations of the medullary e ...... mic epithelial differentiation
@en
Alterations of the medullary e ...... ic epithelial differentiation.
@nl
P2860
P1476
Alterations of the medullary e ...... mic epithelial differentiation
@en
P2093
Andrew G Farr
Matthew Erickson
P2860
P304
P356
10.4049/JIMMUNOL.181.8.5225
P407
P50
P577
2008-10-01T00:00:00Z