IL-23 promotes maintenance but not commitment to the Th17 lineage - Wikidata - wikimedia - TriplyDB

IL-23 promotes maintenance but not commitment to the Th17 lineage

IL-23 promotes maintenance but not commitment to the Th17 lineage

http://www.wikidata.org/entity/Q37183888

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Interleukin-23: as a drug target for autoimmune inflammatory diseases Design of a superior cytokine antagonist for topical ophthalmic use Understanding Immune Cells in Tertiary Lymphoid Organ Development: It Is All Starting to Come Together Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic Th17 promotes acute rejection following liver transplantation in rats The changes of Th17 cells and the related cytokines in the progression of human colorectal cancers.Human interleukin-23 receptor antagonists derived from an albumin-binding domain scaffold inhibit IL-23-dependent ex vivo expansion of IL-17-producing T-cells β-catenin and PI3Kδ inhibition expands precursor Th17 cells with heightened stemness and antitumor activity.High IL-17 expression is associated with an unfavorable prognosis in thyroid cancer Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis.Interferon-α-conditioned human monocytes combine a Th1-orienting attitude with the induction of autologous Th17 responses: role of IL-23 and IL-12.IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?Current views on the roles of Th1 and Th17 cells in experimental autoimmune encephalomyelitis.Epinephrine-primed murine bone marrow-derived dendritic cells facilitate production of IL-17A and IL-4 but not IFN-γ by CD4+ T cells.Th17 cells demonstrate stable cytokine production in a proallergic environment CD69 association with Jak3/Stat5 proteins regulates Th17 cell differentiation Unlike Th1, Th17 cells mediate sustained autoimmune inflammation and are highly resistant to restimulation-induced cell death Cytokine requirements for the differentiation and expansion of IL-17A- and IL-22-producing human Vgamma2Vdelta2 T cells.Additive effects of combination treatment with anti-inflammatory and neuroprotective agents in experimental autoimmune encephalomyelitis.Stromal cells induce Th17 during Helicobacter pylori infection and in the gastric tumor microenvironment.CD57 expression and cytokine production by T cells in lesional and unaffected skin from patients with psoriasis RORγt, but not T-bet, overexpression exacerbates an autoimmune model for multiple sclerosis.Influenza A inhibits Th17-mediated host defense against bacterial pneumonia in mice Exposure to atmospheric particulate matter enhances Th17 polarization through the aryl hydrocarbon receptor.Dynamic BRG1 recruitment during T helper differentiation and activation reveals distal regulatory elements.The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.Expression of IL-23/Th17 pathway in a murine model of Coxsackie virus B3-induced viral myocarditis.IL12Rβ1: the cytokine receptor that we used to know.Increased frequency of follicular helper T cells in mice viral myocarditis is relevant with anti-ANT antoantibody.Interleukin-17A promotes early but attenuates established disease in crescentic glomerulonephritis in mice.Lactobacillus acidophilus suppresses colitis-associated activation of the IL-23/Th17 axis.The role of cytokines and chemokines in Histoplasma capsulatum infection.Activated human valvular interstitial cells sustain interleukin-17 production to recruit neutrophils in infective endocarditis Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-α therapy Reduced IL-17A Secretion Is Associated with High Levels of Pneumococcal Nasopharyngeal Carriage in Fijian Children.Dendritic Cells in Irradiated Mice Trigger the Functional Plasticity and Antitumor Activity of Adoptively Transferred Tc17 Cells via IL12 Signaling Disparate Effects of Mesenchymal Stem Cells in Experimental Autoimmune Encephalomyelitis and Cuprizone-Induced Demyelination.Leprosy Reactions Show Increased Th17 Cell Activity and Reduced FOXP3+ Tregs with Concomitant Decrease in TGF-β and Increase in IL-6 Concurrent bacterial stimulation alters the function of helminth-activated dendritic cells, resulting in IL-17 induction.The transcriptome of HIV-1 infected intestinal CD4+ T cells exposed to enteric bacteria.

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IL-23 promotes maintenance but not commitment to the Th17 lineage

http://www.wikidata.org/entity/Q37183888

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

IL-23 promotes maintenance but not commitment to the Th17 lineage

@en

IL-23 promotes maintenance but not commitment to the Th17 lineage.

@nl

type

label

IL-23 promotes maintenance but not commitment to the Th17 lineage

@en

IL-23 promotes maintenance but not commitment to the Th17 lineage.

@nl

prefLabel

IL-23 promotes maintenance but not commitment to the Th17 lineage

@en

IL-23 promotes maintenance but not commitment to the Th17 lineage.

@nl

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JIMMUNOL.181.9.5948

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Journal of Immunology

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IL-23 promotes maintenance but not commitment to the Th17 lineage

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P2093

Gretta L Stritesky

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Mark H Kaplan

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Norman Yeh

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P2860

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

STAT3 and NF-kappaB signal pathway is required for IL-23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonist-deficient mice

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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5948-5955

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scholarly article

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10.4049/JIMMUNOL.181.9.5948

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181

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2008-11-01T00:00:00Z

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18941183

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2678905

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