APOBEC3G restricts early HIV-1 replication in the cytoplasm of target cells.
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AID and APOBECs span the gap between innate and adaptive immunityHIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factorsRestriction of retroviral replication by APOBEC3G/F and TRIM5alphaMultiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them allAPOBEC3 Interference during Replication of Viral GenomesMultiple ways of targeting APOBEC3-virion infectivity factor interactions for anti-HIV-1 drug development.HIV-1 Gag-virus-like particles inhibit HIV-1 replication in dendritic cells and T cells through IFN-α-dependent upregulation of APOBEC3G and 3F.APOBEC3G inhibits elongation of HIV-1 reverse transcripts.APOBEC3F and APOBEC3G inhibit HIV-1 DNA integration by different mechanisms.Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoformsN-terminal hemagglutinin tag renders lysine-deficient APOBEC3G resistant to HIV-1 Vif-induced degradation by reduced polyubiquitination.Identification of specific determinants of human APOBEC3F, APOBEC3C, and APOBEC3DE and African green monkey APOBEC3F that interact with HIV-1 Vif.Lower HIV provirus levels are associated with more APOBEC3G protein in blood resting memory CD4+ T lymphocytes of controllers in vivo.SJP-L-5, a novel small-molecule compound, inhibits HIV-1 infection by blocking viral DNA nuclear entry.Minimal Contribution of APOBEC3-Induced G-to-A Hypermutation to HIV-1 Recombination and Genetic Variation.Antiviral Mechanism and Biochemical Basis of the Human APOBEC3 Family.Emerging complexities of APOBEC3G action on immunity and viral fitness during HIV infection and treatment.Suppression of HIV-1 infection by APOBEC3 proteins in primary human CD4(+) T cells is associated with inhibition of processive reverse transcription as well as excessive cytidine deamination.Human immunodeficiency virus type 1 replication and regulation of APOBEC3G by peptidyl prolyl isomerase Pin1.APOBEC proteins and intrinsic resistance to HIV-1 infectionHost Factors and HIV-1 Replication: Clinical Evidence and Potential Therapeutic ApproachesDefining APOBEC3 expression patterns in human tissues and hematopoietic cell subsets.Tumultuous relationship between the human immunodeficiency virus type 1 viral infectivity factor (Vif) and the human APOBEC-3G and APOBEC-3F restriction factors.APOBEC3G-Mediated G-to-A Hypermutation of the HIV-1 Genome: The Missing Link in Antiviral Molecular MechanismsAssociation of single nucleotide polymorphisms of APOBEC3G with susceptibility to HIV-1 infection and disease progression among men engaging in homosexual activity in northern China.Towards Inhibition of Vif-APOBEC3G Interaction: Which Protein to Target?The role of cytidine deaminases on innate immune responses against human viral infections.Cytoplasmic APOBEC3G restricts incoming Vif-positive human immunodeficiency virus type 1 and increases two-long terminal repeat circle formation in activated T-helper-subtype cells.Viral subversion of APOBEC3s: Lessons for anti-tumor immunity and tumor immunotherapy.
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APOBEC3G restricts early HIV-1 replication in the cytoplasm of target cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 March 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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APOBEC3G restricts early HIV-1 replication in the cytoplasm of target cells.
@en
APOBEC3G restricts early HIV-1 replication in the cytoplasm of target cells.
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type
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APOBEC3G restricts early HIV-1 replication in the cytoplasm of target cells.
@en
APOBEC3G restricts early HIV-1 replication in the cytoplasm of target cells.
@nl
prefLabel
APOBEC3G restricts early HIV-1 replication in the cytoplasm of target cells.
@en
APOBEC3G restricts early HIV-1 replication in the cytoplasm of target cells.
@nl
P2860
P1433
P1476
APOBEC3G restricts early HIV-1 replication in the cytoplasm of target cells.
@en
P2093
Thomas J Hope
P2860
P356
10.1016/J.VIROL.2008.01.042
P407
P577
2008-03-04T00:00:00Z