Mitochondrion-associated protein LRPPRC suppresses the initiation of basal levels of autophagy via enhancing Bcl-2 stability.
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Allelic imbalance of somatic mutations in cancer genomes and transcriptomes.Autophagy inhibitor LRPPRC suppresses mitophagy through interaction with mitophagy initiator Parkin.The viral restriction factor tetherin prevents leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) from association with beclin 1 and B-cell CLL/lymphoma 2 (Bcl-2) and enhances autophagy and mitophagy.ZNF32 inhibits autophagy through the mTOR pathway and protects MCF-7 cells from stimulus-induced cell death.Mitochondrial vulnerability and increased susceptibility to nutrient-induced cytotoxicity in fibroblasts from leigh syndrome French canadian patients.The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer's Disease.Transforming Growth Factor TGFβ Increases Levels of Microtubule-Associated Protein MAP1S and Autophagy Flux in Pancreatic Ductal AdenocarcinomasBeclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiologyBlocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin.Potassium Bisperoxo(1,10-phenanthroline)oxovanadate (bpV(phen)) Induces Apoptosis and Pyroptosis and Disrupts the P62-HDAC6 Protein Interaction to Suppress the Acetylated Microtubule-dependent Degradation of Autophagosomes.Defects in MAP1S-mediated autophagy cause reduction in mouse lifespans especially when fibronectin is overexpressedAffinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein.Fast clearance of lipid droplets through MAP1S-activated autophagy suppresses clear cell renal cell carcinomas and promotes patient survivalDefects in MAP1S-mediated autophagy turnover of fibronectin cause renal fibrosis.Autophagy defects suggested by low levels of autophagy activator MAP1S and high levels of autophagy inhibitor LRPPRC predict poor prognosis of prostate cancer patients.Elevated levels of mitochondrion-associated autophagy inhibitor LRPPRC are associated with poor prognosis in patients with prostate cancer.Emerging connections between RNA and autophagy.Mitochondrion-associated protein peroxiredoxin 3 promotes benign prostatic hyperplasia through autophagy suppression and pyroptosis activation.Metastatic prostate cancer-associated P62 inhibits autophagy flux and promotes epithelial to mesenchymal transition by sustaining the level of HDAC6.Neuroprotection Through Rapamycin-Induced Activation of Autophagy and PI3K/Akt1/mTOR/CREB Signaling Against Amyloid-β-Induced Oxidative Stress, Synaptic/Neurotransmission Dysfunction, and Neurodegeneration in Adult Rats.Impact of Premutation on Neurobehavior and Bioenergetics in Young Monozygotic Twins
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P2860
Mitochondrion-associated protein LRPPRC suppresses the initiation of basal levels of autophagy via enhancing Bcl-2 stability.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mitochondrion-associated prote ...... via enhancing Bcl-2 stability.
@en
Mitochondrion-associated prote ...... via enhancing Bcl-2 stability.
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type
label
Mitochondrion-associated prote ...... via enhancing Bcl-2 stability.
@en
Mitochondrion-associated prote ...... via enhancing Bcl-2 stability.
@nl
prefLabel
Mitochondrion-associated prote ...... via enhancing Bcl-2 stability.
@en
Mitochondrion-associated prote ...... via enhancing Bcl-2 stability.
@nl
P2093
P2860
P356
P1433
P1476
Mitochondrion-associated prote ...... via enhancing Bcl-2 stability.
@en
P2093
P2860
P304
P356
10.1042/BJ20130306
P407
P577
2013-09-01T00:00:00Z