Suppression of the MEK/ERK signaling pathway reverses depression-like behaviors of CRF2-deficient mice.
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Depression research: where are we now?Urocortins: CRF's siblings and their potential role in anxiety, depression and alcohol drinking behavior.The role of PKC signaling in CRF-induced modulation of startle.Behavioral Studies and Genetic Alterations in Corticotropin-Releasing Hormone (CRH) Neurocircuitry: Insights into Human Psychiatric Disorders.Role of CRF receptor signaling in stress vulnerability, anxiety, and depression.Sustained AAV-mediated overexpression of CRF in the central amygdala diminishes the depressive-like state associated with nicotine withdrawalAdenosine A2A receptor and ERK-driven impulsivity potentiates hippocampal neuroblast proliferation.B-Raf and CRHR1 internalization mediate biphasic ERK1/2 activation by CRH in hippocampal HT22 Cells.Extracellular signal-regulated kinase-2 within the ventral tegmental area regulates responses to stress.Concomitant interferon alpha stimulation and TLR3 activation induces neuronal expression of depression-related genes that are elevated in the brain of suicidal persons.Evidence demonstrating role of microRNAs in the etiopathology of major depressionProteomic and metabolomic profiling of a trait anxiety mouse model implicate affected pathwaysRegulation of ERK Kinase by MEK1 Kinase Inhibition in the BrainMicroRNA as therapeutic targets for treatment of depression.Transcriptomics in Interferon-α-Treated Patients Identifies Inflammation-, Neuroplasticity- and Oxidative Stress-Related Signatures as Predictors and Correlates of Depression.Hippocampal c-Jun-N-terminal kinases serve as negative regulators of associative learning.The CRF System as a Therapeutic Target for Neuropsychiatric Disorders.Association of KRAS gene mutations with depression in older metastatic colorectal cancer patients.Overexpression of CRF in the BNST diminishes dysphoria but not anxiety-like behavior in nicotine withdrawing rats.CRHR1 Mediates the Up-Regulation of Synapsin I Induced by Nesfatin-1 Through ERK 1/2 Signaling in SH-SY5Y Cells.Fluoxetine signature on hippocampal MAPK signalling in sex-dependent manner.
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Suppression of the MEK/ERK signaling pathway reverses depression-like behaviors of CRF2-deficient mice.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 October 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Suppression of the MEK/ERK sig ...... aviors of CRF2-deficient mice.
@en
Suppression of the MEK/ERK sig ...... aviors of CRF2-deficient mice.
@nl
type
label
Suppression of the MEK/ERK sig ...... aviors of CRF2-deficient mice.
@en
Suppression of the MEK/ERK sig ...... aviors of CRF2-deficient mice.
@nl
prefLabel
Suppression of the MEK/ERK sig ...... aviors of CRF2-deficient mice.
@en
Suppression of the MEK/ERK sig ...... aviors of CRF2-deficient mice.
@nl
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Suppression of the MEK/ERK sig ...... aviors of CRF2-deficient mice.
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Cathrin Hippel
Cedomir Todorovic
Joachim Spiess
Martin Rayner
Matthew Pitts
Tessi Sherrin
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P2888
P304
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10.1038/NPP.2008.178
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P577
2008-10-08T00:00:00Z
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P6179
1021750709