Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size
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Challenges and Opportunities for T-Cell-Mediated Strategies to Eliminate HIV ReservoirsHow does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs?Influence of immune activation and inflammatory response on cardiovascular risk associated with the human immunodeficiency virusDeveloping Combined HIV Vaccine Strategies for a Functional CureImpact of antiretroviral therapy (ART) timing on chronic immune activation/inflammation and end-organ damageHIV and aging: emerging research issuesMight dolutegravir be part of a functional cure for HIV?Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized TrialImmunologic Biomarkers, Morbidity, and Mortality in Treated HIV InfectionProspective Study of Acute HIV-1 Infection in Adults in East Africa and Thailand.HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality.Identification of Acute HIV-1 Infection by Hologic Aptima HIV-1 RNA Qualitative Assay.Low proportions of CD28- CD8+ T cells expressing CD57 can be reversed by early ART initiation and predict mortality in treated HIV infection.Can early therapy reduce inflammation?Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection.Antiretroviral treatment of HIV-1 prevents transmission of HIV-1: where do we go from here?Programmed death-1 expression on CD4⁺ and CD8⁺ T cells in treated and untreated HIV disease.Reconstitution of intestinal CD4 and Th17 T cells in antiretroviral therapy suppressed HIV-infected subjects: implication for residual immune activation from the results of a clinical trial.Is the central nervous system a reservoir of HIV-1?HIV vasculopathy: role of mononuclear cell-associated Krüppel-like factors 2 and 4.Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques.Influence of the timing of antiretroviral therapy on the potential for normalization of immune status in human immunodeficiency virus 1-infected individuals.Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activationDecreased HIV type 1 transcription in CCR5-Δ32 heterozygotes during suppressive antiretroviral therapyExploring the potential of monoclonal antibody therapeutics for HIV-1 eradication.Sex, age, race and intervention type in clinical studies of HIV cure: a systematic review.Influence of age at virologic control on peripheral blood human immunodeficiency virus reservoir size and serostatus in perinatally infected adolescentsImpact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging.Choice of antiretroviral therapy differentially impacts survival of HIV-infected CD4 T cellsDelay in cART initiation results in persistent immune dysregulation and poor recovery of T-cell phenotype despite a decade of successful HIV suppression.Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption.Non-coding RNAs and HIV: viral manipulation of host dark matter to shape the cellular environment.Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection.Impact of Early Initiation of Antiretroviral Therapy in Patients with Acute HIV Infection in Vienna, Austria.Establishment and Replenishment of the Viral Reservoir in Perinatally HIV-1-infected Children Initiating Very Early Antiretroviral TherapyDiscordant Immune Response with Antiretroviral Therapy in HIV-1: A Systematic Review of Clinical Outcomes.Quantifying Adaptive and Innate Immune Responses in HIV-Infected Participants Using a Novel High Throughput AssayCD4/CD8 Ratio and KT Ratio Predict Yellow Fever Vaccine Immunogenicity in HIV-Infected PatientsEarly Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA PopulationsPaucity of Intact Non-Induced Provirus with Early, Long-Term Antiretroviral Therapy of Perinatal HIV Infection.
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Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Antiretroviral therapy initiat ...... and smaller HIV reservoir size
@en
Antiretroviral therapy initiat ...... nd smaller HIV reservoir size.
@nl
type
label
Antiretroviral therapy initiat ...... and smaller HIV reservoir size
@en
Antiretroviral therapy initiat ...... nd smaller HIV reservoir size.
@nl
prefLabel
Antiretroviral therapy initiat ...... and smaller HIV reservoir size
@en
Antiretroviral therapy initiat ...... nd smaller HIV reservoir size.
@nl
P2093
P2860
P50
P356
P1476
Antiretroviral therapy initiat ...... and smaller HIV reservoir size
@en
P2093
Christopher D Pilcher
Elizabeth Sinclair
Hiroyu Hatano
Joseph M McCune
Lorrie Epling
Peter Bacchetti
Peter W Hunt
Vivek Jain
Wendy Hartogensis
P2860
P304
P356
10.1093/INFDIS/JIT311
P407
P577
2013-07-12T00:00:00Z