The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival. - Wikidata - wikimedia - TriplyDB

The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival.

The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival.

http://www.wikidata.org/entity/Q37192095

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The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells Ribosomopathies: how a common root can cause a tree of pathologies Guarding the 'translation apparatus': defective ribosome biogenesis and the p53 signaling pathway Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes Diverse diseases from a ubiquitous process: the ribosomopathy paradox Role of ribosomal protein mutations in tumor development (Review)Regulatory Roles of Rpl22 in Hematopoiesis: An Old Dog with New Tricks RACK1 depletion in a mouse model causes lethality, pigmentation deficits and reduction in protein synthesis efficiency An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction EMG1 is essential for mouse pre-implantation embryo development p53 pathway is involved in cell competition during mouse embryogenesis siRNA knockdown of ribosomal protein gene RPL19 abrogates the aggressive phenotype of human prostate cancer.Comprehensive fluorogenic derivatization-liquid chromatography/tandem mass spectrometry proteomic analysis of colorectal cancer cell to identify biomarker candidate.Haematopoietic stem cells require a highly regulated protein synthesis rate.p53 upregulation is a frequent response to deficiency of cell-essential genes Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits.Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders.Ribosomal proteins and human diseases: pathogenesis, molecular mechanisms, and therapeutic implications Cellular differences in protein synthesis regulate tissue homeostasis.Ribosomal proteins: functions beyond the ribosome Coordination of progenitor specification and growth in mouse and chick spinal cord Genetics of ribosomal proteins: "curiouser and curiouser"The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling.Ribosomal proteins RPL37, RPS15 and RPS20 regulate the Mdm2-p53-MdmX network The role of Myc-induced protein synthesis in cancer.Animal models of Diamond Blackfan anemia.The Ribosomal Protein-Mdm2-p53 Pathway and Energy Metabolism: Bridging the Gap between Feast and Famine.Hydrophilic residues are crucial for ribosomal protein L11 (RPL11) interaction with zinc finger domain of MDM2 and p53 protein activation In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency.The RP-Mdm2-p53 pathway and tumorigenesis Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis Interplay of H2A deubiquitinase 2A-DUB/Mysm1 and the p19(ARF)/p53 axis in hematopoiesis, early T-cell development and tissue differentiation Important genes in the pathogenesis of 5q- syndrome and their connection with ribosomal stress and the innate immune system pathway.Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress A liaison between mTOR signaling, ribosome biogenesis and cancer RPL27A is a target of miR-595 and may contribute to the myelodysplastic phenotype through ribosomal dysgenesis Translational control in cellular and developmental processes.p53 -Dependent and -Independent Nucleolar Stress Responses.p53, a translational regulator: contribution to its tumour-suppressor activity.

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The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival.

http://www.wikidata.org/entity/Q37192095

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bilimsel makale

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scientific article published on 09 March 2009

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vedecký článok

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The p53 tumor suppressor cause ...... e and promotes their survival.

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The p53 tumor suppressor cause ...... e and promotes their survival.

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The p53 tumor suppressor cause ...... e and promotes their survival.

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The p53 tumor suppressor cause ...... e and promotes their survival.

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The p53 tumor suppressor cause ...... e and promotes their survival.

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The p53 tumor suppressor cause ...... e and promotes their survival.

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Molecular and Cellular Biology

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The p53 tumor suppressor cause ...... ce and promotes their survival

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Ines Jerić

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Ivana Bogetić

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Linda Panić

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Martina Barkić

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Sanda Tamarut

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Sandra Vidak

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Sladana Crnomarković

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P2860

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

Ribosomal protein S17 gene (RPS17) is mutated in Diamond-Blackfan anemia

Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia

Evidence of p53-dependent cross-talk between ribosome biogenesis and the cell cycle: effects of nucleolar protein Bop1 on G(1)/S transition

Repression of RNA polymerase I transcription by the tumor suppressor p53

Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation

Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemia

Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients

Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway

Sequential protein association with nascent 60S ribosomal particles

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2489-2504

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scholarly article

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10.1128/MCB.01588-08

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10

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29

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Sinisa Volarevic

Kristina Grabusic

Maja Cokarić Brdovčak

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2009-03-09T00:00:00Z

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24188913

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19273598

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2682053

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