The block of DNA polymerase delta strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase beta and Flap endonuclease 1.
about
SIRT1 deacetylates TopBP1 and modulates intra-S-phase checkpoint and DNA replication origin firingA 5', 8-cyclo-2'-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase βBypass of a 5',8-cyclopurine-2'-deoxynucleoside by DNA polymerase β during DNA replication and base excision repair leads to nucleotide misinsertions and DNA strand breaks.The use of modified and non-natural nucleotides provide unique insights into pro-mutagenic replication catalyzed by polymerase etaHuman DNA polymerase β, but not λ, can bypass a 2-deoxyribonolactone lesion together with proliferating cell nuclear antigen.Avoidance of APOBEC3B-induced mutation by error-free lesion bypassNon-bulky Lesions in Human DNA: the Ways of Formation, Repair, and Replication.Base excision repair proteins couple activation-induced cytidine deaminase and endonuclease G during replication stress-induced MLL destabilization.
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P2860
The block of DNA polymerase delta strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase beta and Flap endonuclease 1.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The block of DNA polymerase de ...... beta and Flap endonuclease 1.
@en
The block of DNA polymerase de ...... beta and Flap endonuclease 1.
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type
label
The block of DNA polymerase de ...... beta and Flap endonuclease 1.
@en
The block of DNA polymerase de ...... beta and Flap endonuclease 1.
@nl
prefLabel
The block of DNA polymerase de ...... beta and Flap endonuclease 1.
@en
The block of DNA polymerase de ...... beta and Flap endonuclease 1.
@nl
P2093
P2860
P356
P1476
The block of DNA polymerase de ...... beta and Flap endonuclease 1.
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P2093
Giovanni Maga
Giuseppe Villani
Ulrich Hübscher
P2860
P304
14267-14275
P356
10.1074/JBC.M900759200
P407
P577
2009-03-27T00:00:00Z