Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes. - Wikidata - wikimedia - TriplyDB

Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes.

Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes.

http://www.wikidata.org/entity/Q37194718

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Structural basis for cooperative binding of azoles to CYP2E1 as interpreted through guided molecular dynamics simulations.Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates.Functioning of drug-metabolizing microsomal cytochrome P450s: In silico probing of proteins suggests that the distal heme 'active site' pocket plays a relatively 'passive role' in some enzyme-substrate interactions Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like.Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures.Spectroscopic studies of the cytochrome P450 reaction mechanisms.Cytochrome P450 structure-function: insights from molecular dynamics simulations.Biochar application increases sorption of nitrification inhibitor 3,4-dimethylpyrazole phosphate in soil.

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Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes.

http://www.wikidata.org/entity/Q37194718

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

@tr

scientific article published on 27 June 2013

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

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name

Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.

@en

Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.

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type

label

Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.

@en

Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.

@nl

prefLabel

Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.

@en

Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.

@nl

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J.ABB.2013.06.011

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Archives of Biochemistry and Biophysics

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Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.

@en

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Amber M Bradley

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Grover P Miller

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Jessica H Hartman

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Martin D Perry

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Ryan M Laddusaw

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P2860

Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates

Human Cytochrome P450 2E1 Structures with Fatty Acid Analogs Reveal a Previously Unobserved Binding Mode

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CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling.

CYP2E1 metabolism of styrene involves allostery.

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12-20

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scholarly article

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10.1016/J.ABB.2013.06.011

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