The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes
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Melanoma: from melanocyte to genetic alterations and clinical optionsPhytochemicals for the Management of MelanomaThe BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer TherapeuticsCurrent and future trials of targeted therapies in cutaneous melanomaRaf kinases in cancer-roles and therapeutic opportunitiesZebrafish have a competent p53-dependent nucleotide excision repair pathway to resolve ultraviolet B-induced DNA damage in the skin.Role of senescence and mitotic catastrophe in cancer therapy.Molecular pathogenesis of sporadic melanoma and melanoma-initiating cells.P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferationHigh-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assaysMechanisms of chromosomal instability in melanoma.BRAF drives synovial fibroblast transformation in rheumatoid arthritis.Artificial skin in perspective: concepts and applications.The three-dimensional human skin reconstruct model: a tool to study normal skin and melanoma progressionThree-dimensional modeling of ovarian cancer.Snail1 mediates hypoxia-induced melanoma progressionCellular senescence and cancer chemotherapy resistance.A prognostic signature of defective p53-dependent G1 checkpoint function in melanoma cell linesMicroRNA-3151 inactivates TP53 in BRAF-mutated human malignancies.Effective intra-S checkpoint responses to UVC in primary human melanocytes and melanoma cell linesHuman skin neural crest progenitor cells are susceptible to BRAF(V600E)-induced transformationInduction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways.The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival.Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cellsTargeting the MAPK pathway in melanoma: why some approaches succeed and other fail.The role of mitogen- and stress-activated protein kinase pathways in melanoma.Narrowing the knowledge gaps for melanomaThe role of AKT/mTOR pathway in stress response to UV-irradiation: implication in skin carcinogenesis by regulation of apoptosis, autophagy and senescenceRestoring the tumour suppressive function of p53 as a parallel strategy in melanoma therapy.Establishment and characterization of a primary and a metastatic melanoma cell line from Grey horses.Interaction of mutant hepatitis B X protein with p53 tumor suppressor protein affects both transcription and cell survival.p53 prevents progression of nevi to melanoma predominantly through cell cycle regulationPrognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known BRAF mutation status.Role for IGFBP7 in senescence induction by BRAF.Cancer modeling by Transgene Electroporation in Adult Zebrafish (TEAZ)
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The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 23 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The role of BRAF mutation and ...... n of primary human melanocytes
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The role of BRAF mutation and ...... of primary human melanocytes.
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type
label
The role of BRAF mutation and ...... n of primary human melanocytes
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The role of BRAF mutation and ...... of primary human melanocytes.
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prefLabel
The role of BRAF mutation and ...... n of primary human melanocytes
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The role of BRAF mutation and ...... of primary human melanocytes.
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P2860
P1476
The role of BRAF mutation and ...... n of primary human melanocytes
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David E Elder
Katharine L Nathanson
Maria Dalla Palma
Matt Guerra
Patricia Possik
Patricia Van Belle
Phyllis Gimotty
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P304
P356
10.2353/AJPATH.2009.081057
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P577
2009-04-23T00:00:00Z