Inhibition of P-glycoprotein-mediated paclitaxel resistance by reversibly linked quinine homodimers
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Overcoming drug efflux-based multidrug resistance in cancer with nanotechnologyNanomedicine therapeutic approaches to overcome cancer drug resistanceThe Alterations in the Expression and Function of P-Glycoprotein in Vitamin A-Deficient Rats as well as the Effect of Drug Disposition in VivoCombined effects of epileptic seizure and phenobarbital induced overexpression of P-glycoprotein in brain of chemically kindled ratsQuinine dimers are potent inhibitors of the Plasmodium falciparum chloroquine resistance transporter and are active against quinoline-resistant P. falciparumBiomechanics and thermodynamics of nanoparticle interactions with plasma and endosomal membrane lipids in cellular uptake and endosomal escape.Dimeric Cinchona alkaloids4-Isoxazolyl-1,4-dihydropyridines exhibit binding at the multidrug-resistance transporterFluorescent probes of the isoxazole-dihydropyridine scaffold: MDR-1 binding and homology model.Reversible dimers of the atypical antipsychotic quetiapine inhibit p-glycoprotein-mediated efflux in vitro with increased binding affinity and in situ at the blood-brain barrier.Tissue-specific alterations in expression and function of P-glycoprotein in streptozotocin-induced diabetic rats.Interactions of dietary phytochemicals with ABC transporters: possible implications for drug disposition and multidrug resistance in cancer.4-isoxazolyl-1,4-dihydropyridines: a tale of two scaffolds.Pregnane X receptors regulate CYP2C8 and P-glycoprotein to impact on the resistance of NSCLC cells to Taxol.Advances in plant-based inhibitors of P-glycoprotein.In vitro and in silico analysis of the vascular effects of asymmetrical N,N-bis(alkanol)amine aryl esters, novel multidrug resistance-reverting agents.A multivalent probe for AI-2 quorum-sensing receptorsHydrocinchonine, cinchonine, and quinidine potentiate paclitaxel-induced cytotoxicity and apoptosis via multidrug resistance reversal in MES-SA/DX5 uterine sarcoma cells.Inhibition of human P-glycoprotein transport and substrate binding using a galantamine dimer.Micro-RNA149 Confers Taxane Resistance to Malignant Mesothelioma Cells via Regulation of P-glycoprotein Expression.Dimeric isoxazolyl-1,4-dihydropyridines have enhanced binding at the multi-drug resistance transporter.Increased Expression of P-Glycoprotein Is Associated With Chlorpyrifos Resistance in the German Cockroach (Blattodea: Blattellidae).Taxane resistance in castration-resistant prostate cancer: mechanisms and therapeutic strategies
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P2860
Inhibition of P-glycoprotein-mediated paclitaxel resistance by reversibly linked quinine homodimers
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 22 October 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Inhibition of P-glycoprotein-m ...... ibly linked quinine homodimers
@en
Inhibition of P-glycoprotein-m ...... bly linked quinine homodimers.
@nl
type
label
Inhibition of P-glycoprotein-m ...... ibly linked quinine homodimers
@en
Inhibition of P-glycoprotein-m ...... bly linked quinine homodimers.
@nl
prefLabel
Inhibition of P-glycoprotein-m ...... ibly linked quinine homodimers
@en
Inhibition of P-glycoprotein-m ...... bly linked quinine homodimers.
@nl
P2093
P2860
P356
P1476
Inhibition of P-glycoprotein-m ...... ibly linked quinine homodimers
@en
P2093
Christine A Hrycyna
Dana Emmert
Jean Chmielewski
Marcos M Pires
P2860
P304
P356
10.1124/MOL.108.050492
P577
2008-10-22T00:00:00Z