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Antibiotics and RNase PtRNAs as antibiotic targetsCharge reduction and thermodynamic stabilization of substrate RNAs inhibit RNA editingRapid identification and characterization of hammerhead-ribozyme inhibitors using fluorescence-based technology.Two-dimensional combinatorial screening identifies specific 6'-acylated kanamycin A- and 6'-acylated neamine-RNA hairpin interactions.Genome-wide characterisation of the binding repertoire of small molecule drugs.Ribosomal protein S12 and aminoglycoside antibiotics modulate A-site mRNA cleavage and transfer-messenger RNA activity in Escherichia coliNeomycin-neomycin dimer: an all-carbohydrate scaffold with high affinity for AT-rich DNA duplexes.Recognition of HIV TAR RNA by triazole linked neomycin dimers.Microfluidic compartmentalized directed evolution.Aminoglycoside modifying enzymes.Inhibition of protein synthesis by aminoglycoside-arginine conjugates.A real-time fluorescence polarization activity assay to screen for inhibitors of bacterial ribonuclease PRiboswitches: discovery of drugs that target bacterial gene-regulatory RNAs.Neomycin Sulfate Improves the Antimicrobial Activity of Mupirocin-Based Antibacterial Ointments.Using pyrene-labeled HIV-1 TAR to measure RNA-small molecule binding.Studies on the mechanism of inhibition of bacterial ribonuclease P by aminoglycoside derivatives.Rise and dissemination of aminoglycoside resistance: the aac(6')-Ib paradigm.Insight into the mechanisms of aminoglycoside derivatives interaction with HIV-1 entry steps and viral gene transcription.Aminoglycosides: molecular insights on the recognition of RNA and aminoglycoside mimics.An adaptable pentaloop defines a robust neomycin-B RNA aptamer with conditional ligand-bound structures.A peptide nucleic acid-aminosugar conjugate targeting transactivation response element of HIV-1 RNA genome shows a high bioavailability in human cells and strongly inhibits tat-mediated transactivation of HIV-1 transcriptionInhibition of Klenow DNA polymerase and poly(A)-specific ribonuclease by aminoglycosidesMonitoring the structure of Escherichia coli RNase P RNA in the presence of various divalent metal ions.Some nontoxic metal-based drugs for selected prevalent tropical pathogenic diseases.Inhibition of Bacterial RNase P RNA by Phenothiazine Derivatives.Bacterial type B RNase P: functional characterization of the L5.1-L15.1 tertiary contact and antisense inhibitionInhibition of nuclear pre-mRNA splicing by antibiotics in vitro.Inhibition of bacterial RNase P by aminoglycoside-arginine conjugates.Inhibition of transfer messenger RNA aminoacylation and trans-translation by aminoglycoside antibiotics.Various effects of paromomycin on tmRNA-directed trans-translation.Aminoglycoside interactions and impacts on the eukaryotic ribosome.Capreomycin and hygromycin B modulate the catalytic activity of the delta ribozyme in a manner that depends on the protonation and complexation with Cu2+ ions of these antibiotics.Fluorescence-Based Real-Time Activity Assays to Identify RNase P Inhibitors.Inhibition of eukaryotic ribonuclease P activity by aminoglycosides: kinetic studies.Amikacin: Uses, Resistance, and Prospects for Inhibition.Insight into the role of histidine in RNR motif of protein component of RNase P of M. tuberculosis in catalysis.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1999
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Inhibition of RNase P RNA cleavage by aminoglycosides
@en
Inhibition of RNase P RNA cleavage by aminoglycosides.
@nl
type
label
Inhibition of RNase P RNA cleavage by aminoglycosides
@en
Inhibition of RNase P RNA cleavage by aminoglycosides.
@nl
prefLabel
Inhibition of RNase P RNA cleavage by aminoglycosides
@en
Inhibition of RNase P RNA cleavage by aminoglycosides.
@nl
P2093
P2860
P356
P1476
Inhibition of RNase P RNA cleavage by aminoglycosides
@en
P2093
Brännvall M
Kirsebom LA
Mikkelsen NE
Virtanen A
P2860
P304
P356
10.1073/PNAS.96.11.6155
P407
P577
1999-05-01T00:00:00Z