In vitro analysis of Hrd1p-mediated retrotranslocation of its multispanning membrane substrate 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase.
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Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ERRecent technical developments in the study of ER-associated degradationThe delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyKey steps in ERAD of luminal ER proteins reconstituted with purified componentsCytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1Arms Race between Enveloped Viruses and the Host ERAD MachineryCleaning up in the endoplasmic reticulum: ubiquitin in chargeThe AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnoverA Mighty "Protein Extractor" of the Cell: Structure and Function of the p97/CDC48 ATPase.Sequential actions of the AAA-ATPase valosin-containing protein (VCP)/p97 and the proteasome 19 S regulatory particle in sterol-accelerated, endoplasmic reticulum (ER)-associated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets.A nucleus-based quality control mechanism for cytosolic proteinsControl of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductaseProtein folding and quality control in the endoplasmic reticulum: Recent lessons from yeast and mammalian cell systems.Ubiquitin-dependent protein degradation at the yeast endoplasmic reticulum and nuclear envelope.Importin beta interacts with the endoplasmic reticulum-associated degradation machinery and promotes ubiquitination and degradation of mutant alpha1-antitrypsinProteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy.Proteasome 19S RP binding to the Sec61 channel plays a key role in ERAD.Subcellular Fractionation Analysis of the Extraction of Ubiquitinated Polytopic Membrane Substrate during ER-Associated DegradationThe endoplasmic reticulum-associated degradation pathways of budding yeast.Cleaning up: ER-associated degradation to the rescue.Insulin-induced gene protein (INSIG)-dependent sterol regulation of Hmg2 endoplasmic reticulum-associated degradation (ERAD) in yeast.Structure and function of the AAA+ ATPase p97/Cdc48p.A stalled retrotranslocation complex reveals physical linkage between substrate recognition and proteasomal degradation during ER-associated degradationDirect and essential function for Hrd3 in ER-associated degradation.Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cellsSubstrate-specific mediators of ER associated degradation (ERAD).Geranylgeranyl pyrophosphate is a potent regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA reductase degradation in yeast.Proteolytic regulation of metabolic enzymes by E3 ubiquitin ligase complexes: lessons from yeast.Glycosylation-directed quality control of protein folding.Membrane Protein Quantity Control at the Endoplasmic Reticulum.Dislocation of HMG-CoA reductase and Insig-1, two polytopic endoplasmic reticulum proteins, en route to proteasomal degradation.Transmembrane helix hydrophobicity is an energetic barrier during the retrotranslocation of integral membrane ERAD substratesSterol metabolism regulates neuroserpin polymer degradation in the absence of the unfolded protein response in the dementia FENIB.Positive genetic interactors of HMG2 identify a new set of genetic perturbations for improving sesquiterpene production in Saccharomyces cerevisiae.Innate sensing of influenza A virus hemagglutinin glycoproteins by the host endoplasmic reticulum (ER) stress pathway triggers a potent antiviral response via ER-associated protein degradation.A Cdc48 "Retrochaperone" Function Is Required for the Solubility of Retrotranslocated, Integral Membrane Endoplasmic Reticulum-associated Degradation (ERAD-M) Substrates.The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins.
P2860
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P2860
In vitro analysis of Hrd1p-mediated retrotranslocation of its multispanning membrane substrate 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 26 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
In vitro analysis of Hrd1p-med ...... lglutaryl (HMG)-CoA reductase.
@en
In vitro analysis of Hrd1p-med ...... ate 3-hydroxy-3-methylglutaryl
@nl
type
label
In vitro analysis of Hrd1p-med ...... lglutaryl (HMG)-CoA reductase.
@en
In vitro analysis of Hrd1p-med ...... ate 3-hydroxy-3-methylglutaryl
@nl
prefLabel
In vitro analysis of Hrd1p-med ...... lglutaryl (HMG)-CoA reductase.
@en
In vitro analysis of Hrd1p-med ...... ate 3-hydroxy-3-methylglutaryl
@nl
P2093
P2860
P356
P1476
In vitro analysis of Hrd1p-med ...... lglutaryl (HMG)-CoA reductase.
@en
P2093
Brian K Sato
Randolph Y Hampton
Renee M Garza
P2860
P304
14710-14722
P356
10.1074/JBC.M809607200
P407
P577
2009-03-26T00:00:00Z