Antifungal activities of natural and synthetic iron chelators alone and in combination with azole and polyene antibiotics against Aspergillus fumigatus.
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Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesAlginate oligosaccharides inhibit fungal cell growth and potentiate the activity of antifungals against Candida and Aspergillus sppSiderophores; iron scavengers: the novel & promising targets for pathogen specific antifungal therapy.The iron chelator deferasirox enhances liposomal amphotericin B efficacy in treating murine invasive pulmonary aspergillosis.Targeting iron acquisition blocks infection with the fungal pathogens Aspergillus fumigatus and Fusarium oxysporumIron homeostasis--Achilles' heel of Aspergillus fumigatus?Iron - A Key Nexus in the Virulence of Aspergillus fumigatus.Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus.Effects of Iron Chelators on the Formation and Development of Aspergillus fumigatus Biofilm.Targeting iron assimilation to develop new antibacterials.A defect in iron uptake enhances the susceptibility of Cryptococcus neoformans to azole antifungal drugs.An encapsulation of iron homeostasis and virulence in Cryptococcus neoformans.Protein expression profiles distinguish between experimental invasive pulmonary aspergillosis and Pseudomonas pneumonia.Combined therapy of iron chelator and antioxidant completely restores brain dysfunction induced by iron toxicity.Transcriptome and network analyses in Saccharomyces cerevisiae reveal that amphotericin B and lactoferrin synergy disrupt metal homeostasis and stress response.Addressing current medical needs in invasive fungal infection prevention and treatment with new antifungal agents, strategies and formulations.Zinc acquisition: a key aspect in Aspergillus fumigatus virulence.Antimicrobial peptides: an alternative for innovative medicines?Lactoferrin: Balancing Ups and Downs of Inflammation Due to Microbial Infections.Application of mass spectrometry to elucidate the pathophysiology of Encephalitozoon cuniculi infection in rabbits.Administration of Zinc Chelators Improves Survival of Mice Infected with Aspergillus fumigatus both in Monotherapy and in Combination with Caspofungin.Targeting zinc homeostasis to combat Aspergillus fumigatus infections.Antibacterial activities of iron chelators against common nosocomial pathogens.Chemosensitization as a means to augment commercial antifungal agents.The role of iron and chelators on infections in iron overload and non iron loaded conditions: prospects for the design of new antimicrobial therapies.Identification of membrane proteome of Paracoccidioides lutzii and its regulation by zinc.Anti-cancer iron(II) complexes of pentadentate N-donor ligands: cytotoxicity, transcriptomics analyses, and mechanisms of action.Comparative study on the liquid chromatographic enantioseparation of cyclic β-amino acids and the related cyclic β-aminohydroxamic acids on Cinchona alkaloid-based zwitterionic chiral stationary phases.Microhemorrhage-associated tissue iron enhances the risk for Aspergillus fumigatus invasion in a mouse model of airway transplantation.
P2860
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P2860
Antifungal activities of natural and synthetic iron chelators alone and in combination with azole and polyene antibiotics against Aspergillus fumigatus.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 March 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Antifungal activities of natur ...... against Aspergillus fumigatus.
@en
Antifungal activities of natur ...... against Aspergillus fumigatus.
@nl
type
label
Antifungal activities of natur ...... against Aspergillus fumigatus.
@en
Antifungal activities of natur ...... against Aspergillus fumigatus.
@nl
prefLabel
Antifungal activities of natur ...... against Aspergillus fumigatus.
@en
Antifungal activities of natur ...... against Aspergillus fumigatus.
@nl
P2093
P2860
P356
P1476
Antifungal activities of natur ...... against Aspergillus fumigatus
@en
P2093
Anna R Cruz
Chiung-Yu Huang
John I Gallin
P2860
P304
P356
10.1128/AAC.01547-08
P407
P577
2009-03-23T00:00:00Z