Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44high/cd24low population which is invasive and resistant to anoikis
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Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells.The effects of diet induced obesity on breast cancer associated pathways in mice deficient in SFRP1.SFRP1 reduction results in an increased sensitivity to TGF-β signaling.Regulation of early growth response 2 expression by secreted frizzled related protein 1SOST and DKK: Antagonists of LRP Family Signaling as Targets for Treating Bone Disease.Loss of SFRP1 promotes ductal branching in the murine mammary gland.Key signaling nodes in mammary gland development and cancer: β-catenin.Mitochondrial dysfunction impairs tumor suppressor p53 expression/function.Mice deficient in Sfrp1 exhibit increased adiposity, dysregulated glucose metabolism, and enhanced macrophage infiltrationThe role of the basal stem cell of the human breast in normal development and cancer.Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesisEpithelial cells captured from ductal carcinoma in situ reveal a gene expression signature associated with progression to invasive breast cancerParity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epitheliumOncogenic transformation of mammary epithelial cells by transforming growth factor beta independent of mammary stem cell regulationHuman papillomavirus genotyping and integration in ovarian cancer Saudi patients.An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530).Ductal carcinoma in situ of the breast: morphological and molecular features implicated in progression.MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation.Role of canonical Wnt signaling in endometrial carcinogenesis.Epithelial-mesenchymal transition, the tumor microenvironment, and metastatic behavior of epithelial malignancies.Estrogen-mediated signaling is differentially affected by the expression levels of Sfrp1 in mammary epithelial cells.Tumor suppressor miR-1 inhibits tumor growth and metastasis by simultaneously targeting multiple genes.Subtype-specific alterations of the Wnt signaling pathway in breast cancer: clinical and prognostic significance.Tumour supressor secreted frizzled related protein 1 regulates p53-mediated apoptosis.
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P2860
Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44high/cd24low population which is invasive and resistant to anoikis
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 07 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Down-regulation of sfrp1 in a ...... asive and resistant to anoikis
@en
Down-regulation of sfrp1 in a ...... sive and resistant to anoikis.
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type
label
Down-regulation of sfrp1 in a ...... asive and resistant to anoikis
@en
Down-regulation of sfrp1 in a ...... sive and resistant to anoikis.
@nl
prefLabel
Down-regulation of sfrp1 in a ...... asive and resistant to anoikis
@en
Down-regulation of sfrp1 in a ...... sive and resistant to anoikis.
@nl
P2093
P2860
P356
P1476
Down-regulation of sfrp1 in a ...... asive and resistant to anoikis
@en
P2093
Jeremy M Hugh
Kelly J Gauger
Melissa A Troester
Sallie Smith Schneider
P2860
P2888
P356
10.1186/1475-2867-9-11
P577
2009-05-07T00:00:00Z
P5875
P6179
1001641433