LKB1 catalytic activity contributes to estrogen receptor alpha signaling
about
Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesisThe orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPKMechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.Loss of LKB1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathwaysLiver kinase B1 (LKB1) in the pathogenesis of epithelial cancersPre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss.Loss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion.Oestrogen receptors interact with the α-catalytic subunit of AMP-activated protein kinase.Expression and transcriptional profiling of the LKB1 tumor suppressor in cervical cancer cellsClinical Relevance of Liver Kinase B1(LKB1) Protein and Gene Expression in Breast CancerLarge-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.The LKB1 complex-AMPK pathway: the tree that hides the forestLKB1 suppresses proliferation and invasion of prostate cancer through hedgehog signaling pathway.LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer.Localization-specific LKB1 loss in head and neck squamous cell carcinoma metastasis.Isolated and combined action of tamoxifen and metformin in wild-type, tamoxifen-resistant, and estrogen-deprived MCF-7 cells.Omega-3 polyunsaturated fatty acid promotes the inhibition of glycolytic enzymes and mTOR signaling by regulating the tumor suppressor LKB1Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3.Expression of STK11 gene and its promoter activity in MCF control and cancer cells.
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LKB1 catalytic activity contributes to estrogen receptor alpha signaling
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 15 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
LKB1 catalytic activity contributes to estrogen receptor alpha signaling
@en
LKB1 catalytic activity contributes to estrogen receptor alpha signaling.
@nl
type
label
LKB1 catalytic activity contributes to estrogen receptor alpha signaling
@en
LKB1 catalytic activity contributes to estrogen receptor alpha signaling.
@nl
prefLabel
LKB1 catalytic activity contributes to estrogen receptor alpha signaling
@en
LKB1 catalytic activity contributes to estrogen receptor alpha signaling.
@nl
P2860
P356
P1476
LKB1 catalytic activity contributes to estrogen receptor alpha signaling
@en
P2093
Paola A Marignani
Suchita Nath-Sain
P2860
P304
P356
10.1091/MBC.E08-11-1138
P577
2009-04-15T00:00:00Z