Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells.
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H2 control of natural T regulatory cell frequency in the lymph node correlates with susceptibility to day 3 thymectomy-induced autoimmune diseaseA Bayesian Semi-parametric Approach for the Differential Analysis of Sequence Counts Data.Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis.Model for comparative analysis of antigen receptor repertoires.Reduction of T cell receptor diversity in NOD mice prevents development of type 1 diabetes but not Sjögren's syndrome.Single-cell mass cytometry of TCR signaling: amplification of small initial differences results in low ERK activation in NOD miceThymic negative selection is functional in NOD mice.Estimating T-cell repertoire diversity: limitations of classical estimators and a new approach.Determinants of public T cell responses.The T-cell receptor is not hardwired to engage MHC ligands.CTLA-4 controls the thymic development of both conventional and regulatory T cells through modulation of the TCR repertoire.T cell populations in the pancreatic lymph node naturally and consistently expand and contract in NOD mice as disease progresses.TCR diversity and Treg cells, sometimes more is more.Modeling the T cell immune response: a fascinating challenge.Reversible lacrimal gland-protective regulatory T-cell dysfunction underlies male-specific autoimmune dacryoadenitis in the non-obese diabetic mouse model of Sjögren syndrome.T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.Type 1 Diabetes: A Chronic Anti-Self-Inflammatory Response.Decreased frequencies of CD4+CD25+Foxp3+ cells and the potent CD103+ subset in peripheral lymph nodes correlate with autoimmune disease predisposition in some strains of mice.Patients with CD3G mutations reveal a role for human CD3γ in Treg diversity and suppressive function.Thymic B Cell-Mediated Attack of Thymic Stroma Precedes Type 1 Diabetes Development.High TCR diversity ensures optimal function andhomeostasis of Foxp3+regulatory Tcells
P2860
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P2860
Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells.
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Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells.
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type
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Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells.
@en
Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells.
@nl
prefLabel
Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells.
@en
Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells.
@nl
P2093
P2860
P356
P1476
Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells.
@en
P2093
Anna L Furmanski
Cristina Ferreira
F Susan Wong
Julian Dyson
Oliver A Garden
Yogesh Singh
P2860
P304
P356
10.1073/PNAS.0808493106
P407
P577
2009-04-09T00:00:00Z