A four-column theory for the origin of the genetic code: tracing the evolutionary pathways that gave rise to an optimized code.
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Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach)Anticodon Modifications in the tRNA Set of LUCA and the Fundamental Regularity in the Standard Genetic CodeCoevolution Theory of the Genetic Code at Age Forty: Pathway to Translation and Synthetic LifeHow amino acids and peptides shaped the RNA worldAmino acid fermentation at the origin of the genetic codeOn Nature's Strategy for Assigning Genetic Code Multiplicity.Frozen, but no accident - why the 20 standard amino acids were selected.Exceptional error minimization in putative primordial genetic codes.Effect of correlated tRNA abundances on translation errors and evolution of codon usage biasSimulated evolution applied to study the genetic code optimality using a model of codon reassignments.Frozen Accident Pushing 50: Stereochemistry, Expansion, and Chance in the Evolution of the Genetic Code.Pathways of Genetic Code Evolution in Ancient and Modern Organisms.CMCpy: Genetic Code-Message Coevolution Models in Python.Inclusion of the fitness sharing technique in an evolutionary algorithm to analyze the fitness landscape of the genetic code adaptabilityOn the Origin of Sequence.Self-Referential Encoding on Modules of Anticodon Pairs-Roots of the Biological Flow System.The Hypothesis that the Genetic Code Originated in Coupled Synthesis of Proteins and the Evolutionary Predecessors of Nucleic Acids in Primitive Cells.Revisiting the physico-chemical hypothesis of code origin: an analysis based on code-sequence coevolution in a finite population.Selection on GGU and CGU codons in the high expression genes in bacteria.An Autotrophic Origin for the Coded Amino Acids is Concordant with the Coevolution Theory of the Genetic Code.Ancestral Reconstruction of a Pre-LUCA Aminoacyl-tRNA Synthetase Ancestor Supports the Late Addition of Trp to the Genetic Code.Two perspectives on the origin of the standard genetic code.An alternative look at code evolution: using non-canonical codes to evaluate adaptive and historic models for the origin of the genetic code.A realistic model under which the genetic code is optimal.Comprehensive reduction of amino acid set in a protein suggests the importance of prebiotic amino acids for stable proteins.Horizontal transfer of code fragments between protocells can explain the origins of the genetic code without vertical descent.Analysis of the optimality of the standard genetic code.Evolution of the genetic code by incorporation of amino acids that improved or changed protein function.On the efficiency of the genetic code after frameshift mutations.Genetic Code Evolution Started with the Incorporation of Glycine, Followed by Other Small Hydrophilic Amino AcidsOptimization of the standard genetic code according to three codon positions using an evolutionary algorithm
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A four-column theory for the origin of the genetic code: tracing the evolutionary pathways that gave rise to an optimized code.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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A four-column theory for the o ...... ave rise to an optimized code.
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A four-column theory for the o ...... ave rise to an optimized code.
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A four-column theory for the o ...... ave rise to an optimized code.
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A four-column theory for the o ...... ave rise to an optimized code.
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A four-column theory for the o ...... ave rise to an optimized code.
@en
A four-column theory for the o ...... ave rise to an optimized code.
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P2860
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A four-column theory for the o ...... ave rise to an optimized code.
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Paul G Higgs
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P2888
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10.1186/1745-6150-4-16
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2009-04-24T00:00:00Z
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P6179
1007846730