Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia.
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R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoidsPolymodal activation of the endocannabinoid system in the extended amygdalaThe localization and physiological effects of cannabinoid receptor 1 in the brain stem auditory system of the chickSocial isolation and chronic handling alter endocannabinoid signaling and behavioral reactivity to context in adult ratsCannabinoid CB1 receptor facilitation of substance P release in the rat spinal cord, measured as neurokinin 1 receptor internalization.Endocannabinoids Have Opposing Effects On Behavioral Responses To Nociceptive And Non-nociceptive Stimuli.Multiple functions of endocannabinoid signaling in the brain.Endocannabinoid-dependent LTD in a nociceptive synapse requires activation of a presynaptic TRPV-like receptor.The major central endocannabinoid directly acts at GABA(A) receptors.Capsaicin in the periaqueductal gray induces analgesia via metabotropic glutamate receptor-mediated endocannabinoid retrograde disinhibitionEndocannabinoids and acute pain after total knee arthroplasty.Injury-Dependent and Disability-Specific Lumbar Spinal Gene Regulation following Sciatic Nerve Injury in the RatUltrastructural evidence for synaptic contacts between cortical noradrenergic afferents and endocannabinoid-synthesizing post-synaptic neurons.Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons.Brain 2-Arachidonoylglycerol Levels Are Dramatically and Rapidly Increased Under Acute Ischemia-Injury Which Is Prevented by Microwave Irradiation.Endocannabinoid-dependent long-term depression in a nociceptive synapse requires coordinated presynaptic and postsynaptic transcription and translationComplementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampusDifferential distribution of diacylglycerol lipase-alpha and N-acylphosphatidylethanolamine-specific phospholipase d immunoreactivity in the superficial spinal dorsal horn of rats.Characterisation of cannabinoid 1 receptor expression in the perikarya, and peripheral and spinal processes of primary sensory neurons.A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolaseMore surprises lying ahead. The endocannabinoids keep us guessing.Nonnociceptive afferent activity depresses nocifensive behavior and nociceptive synapses via an endocannabinoid-dependent mechanism.Dynamic regulation of the endocannabinoid system: implications for analgesia.Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord.DAGL-dependent endocannabinoid signalling: roles in axonal pathfinding, synaptic plasticity and adult neurogenesis.The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signallingDynamic changes to the endocannabinoid system in models of chronic pain.The molecular interplay between endocannabinoid and neurotrophin signals in the nervous system and beyond.No more pain upon Gq-protein-coupled receptor activation: role of endocannabinoids.Cannabinoids in pain management: CB1, CB2 and non-classic receptor ligands.The cannabinoid system and pain.Peripheral inflammation affects modulation of nociceptive synaptic transmission in the spinal cord induced by N-arachidonoylphosphatidylethanolamine.Dissecting the Signaling Pathways Involved in the Crosstalk between Metabotropic Glutamate 5 and Cannabinoid Type 1 Receptors.Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia.Re-branding cannabis: the next generation of chronic pain medicine?Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat.A cell population that strongly expresses the CB1 cannabinoid receptor in the ependyma of the rat spinal cord.Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis painEndocannabinoid-dependent plasticity at spinal nociceptor synapses.Selective axonal and glial distribution of monoacylglycerol lipase immunoreactivity in the superficial spinal dorsal horn of rodents.
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Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Molecular architecture of endo ...... synapses mediating analgesia.
@en
Molecular architecture of endo ...... synapses mediating analgesia.
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type
label
Molecular architecture of endo ...... synapses mediating analgesia.
@en
Molecular architecture of endo ...... synapses mediating analgesia.
@nl
prefLabel
Molecular architecture of endo ...... synapses mediating analgesia.
@en
Molecular architecture of endo ...... synapses mediating analgesia.
@nl
P2093
P2860
P50
P1476
Molecular architecture of endo ...... e synapses mediating analgesia
@en
P2093
Andrea G Hohmann
Andreas Zimmer
Laura C Gregg
Masahiko Watanabe
P2860
P304
P356
10.1111/J.1460-9568.2009.06751.X
P407
P577
2009-05-09T00:00:00Z