Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cells - Wikidata - wikimedia - TriplyDB

Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cells

Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cells

http://www.wikidata.org/entity/Q37216909

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Cilia functions in development Purinergic signalling in the kidney in health and disease Role of TRPC3 channels in ATP-induced Ca2+ signaling in principal cells of the inner medullary collecting duct.Adult human CD133/1(+) kidney cells isolated from papilla integrate into developing kidney tubules Cilioplasm is a cellular compartment for calcium signaling in response to mechanical and chemical stimuli.Shear stress-induced volume decrease in C11-MDCK cells by BK-alpha/beta4.Hypertension in Autosomal Dominant Polycystic Kidney Disease: A Clinical and Basic Science Perspective The P2X7 receptor supports both life and death in fibrogenic pancreatic stellate cells A telomerase immortalized human proximal tubule cell line with a truncation mutation (Q4004X) in polycystin-1 Coupled ATP and potassium efflux from intercalated cells.Deciphering physiological role of the mechanosensitive TRPV4 channel in the distal nephron.Inhibition of the P2X7 receptor reduces cystogenesis in PKD.Real-time observation of flow-induced cytoskeletal stress in living cells.Polycystic diseases in visceral organs.Vasopressin and disruption of calcium signalling in polycystic kidney disease.Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium.Flow-induced prostaglandin E2 release regulates Na and K transport in the collecting duct Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity.Role of renal TRP channels in physiology and pathology TRPV4 dysfunction promotes renal cystogenesis in autosomal recessive polycystic kidney disease.Discrete control of TRPV4 channel function in the distal nephron by protein kinases A and C.Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD.P2Y2R is a direct target of HIF-1α and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells.Polycystins and renovascular mechanosensory transduction.Calcium-mediated mechanisms of cystic expansion.Primary cilia: highly sophisticated biological sensors.Non-motile primary cilia as fluid shear stress mechanosensors.New treatments for autosomal dominant polycystic kidney disease The primary cilium as sensor of fluid flow: new building blocks to the model. A review in the theme: cell signaling: proteins, pathways and mechanisms.Calcium channels in primary cilia.AVP-stimulated nucleotide secretion in perfused mouse medullary thick ascending limb and cortical collecting duct.Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation.Survivin-induced abnormal ploidy contributes to cystic kidney and aneurysm formation.ATP releasing connexin 30 hemichannels mediate flow-induced calcium signaling in the collecting duct.Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cells.Role of extracellular ATP and P2 receptor signaling in regulating renal cyst growth and interstitial inflammation in polycystic kidney disease.Dopamine receptor type 5 in the primary cilia has dual chemo- and mechano-sensory roles.The Roles of Primary cilia in Polycystic Kidney Disease.The mechanosensitive BKα/β1 channel localizes to cilia of principal cells in rabbit cortical collecting duct (CCD).Deficient transient receptor potential vanilloid type 4 function contributes to compromised [Ca2+]i homeostasis in human autosomal-dominant polycystic kidney disease cells.

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Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cells

http://www.wikidata.org/entity/Q37216909

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 25 February 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Attenuated, flow-induced ATP r ...... an ADPKD cyst epithelial cells

@en

Attenuated, flow-induced ATP r ...... n ADPKD cyst epithelial cells.

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type

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Attenuated, flow-induced ATP r ...... an ADPKD cyst epithelial cells

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Attenuated, flow-induced ATP r ...... n ADPKD cyst epithelial cells.

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prefLabel

Attenuated, flow-induced ATP r ...... an ADPKD cyst epithelial cells

@en

Attenuated, flow-induced ATP r ...... n ADPKD cyst epithelial cells.

@nl

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AJPRENAL.90542.2008

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American Journal of Physiology - Renal Physiology

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Attenuated, flow-induced ATP r ...... an ADPKD cyst epithelial cells

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Angela Wandinger-Ness

http://www.w3.org/2001/XMLSchema#string

Boris E Shmukler

http://www.w3.org/2001/XMLSchema#string

Chang Xu

http://www.w3.org/2001/XMLSchema#string

Elzbieta Kaczmarek

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Katherine Nishimura

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Peter C Harris

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Robert L Bacallao

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Sandro Rossetti

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Seth L Alper

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P2860

Pharmacology of P2X channels

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling

Physiological regulation of ATP release at the apical surface of human airway epithelia

Nucleotide release provides a mechanism for airway surface liquid homeostasis

Control of epithelial transport via luminal P2 receptors.

Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia.

Subcellular localization and trafficking of polycystins.

Cell to cell communication in response to mechanical stress via bilateral release of ATP and UTP in polarized epithelia.

P2X7 and phospholipid signalling: the search of the "missing link" in epithelial cells.

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F1464-76

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scholarly article

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10.1152/AJPRENAL.90542.2008

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6

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296

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2009-02-25T00:00:00Z

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24041680

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19244404

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2692447

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