TFIIH and P-TEFb coordinate transcription with capping enzyme recruitment at specific genes in fission yeast
about
CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1Regulation of mRNA cap methylationGene-specific requirement of RNA polymerase II CTD phosphorylationRecognition of asymmetrically dimethylated arginine by TDRD3The structure and substrate specificity of human Cdk12/Cyclin KHow an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codesStructure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a noncanonical CTD-interacting domain foldThe transcription elongation factor Spt5 influences transcription by RNA polymerase I positively and negatively.Phosphorylation of the yeast Rpb1 C-terminal domain at serines 2, 5, and 7.TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II.Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA StabilizationA positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeastThreonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongationRNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and TemplateProgression through the RNA polymerase II CTD cycleFunctional characterization of a new member of the Cdk9 family in Aspergillus nidulans.DSIF and RNA polymerase II CTD phosphorylation coordinate the recruitment of Rpd3S to actively transcribed genesSeparable functions of the fission yeast Spt5 carboxyl-terminal domain (CTD) in capping enzyme binding and transcription elongation overlap with those of the RNA polymerase II CTDFunctional analysis of the Cdk7.cyclin H.Mat1 complex in mouse embryonic stem cells and embryosRNA polymerase II transcription elongation and Pol II CTD Ser2 phosphorylation: A tail of two kinases.CDK8 is a positive regulator of transcriptional elongation within the serum response network.Myc Regulation of mRNA Cap MethylationFission yeast RNA triphosphatase reads an Spt5 CTD codeCap-binding protein complex links pre-mRNA capping to transcription elongation and alternative splicing through positive transcription elongation factor b (P-TEFb)The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeastGenetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1.Emerging Views on the CTD CodeRNA polymerase II CTD phospho-sites Ser5 and Ser7 govern phosphate homeostasis in fission yeast.Separate domains of fission yeast Cdk9 (P-TEFb) are required for capping enzyme recruitment and primed (Ser7-phosphorylated) Rpb1 carboxyl-terminal domain substrate recognition.Functional interaction of Rpb1 and Spt5 C-terminal domains in co-transcriptional histone modificationThe CDK Network: Linking Cycles of Cell Division and Gene Expression.Divergence of a conserved elongation factor and transcription regulation in budding and fission yeastCyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase IIHuman cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites.Selective control of gene expression by CDK9 in human cellsMolecular pathology of mixed-lineage leukemia.Pause, play, repeat: CDKs push RNAP II's buttons.Chemical genetics: budding yeast as a platform for drug discovery and mapping of genetic pathways.Putting an 'End' to HIV mRNAs: capping and polyadenylation as potential therapeutic targets.
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P2860
TFIIH and P-TEFb coordinate transcription with capping enzyme recruitment at specific genes in fission yeast
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
TFIIH and P-TEFb coordinate tr ...... pecific genes in fission yeast
@en
TFIIH and P-TEFb coordinate tr ...... ecific genes in fission yeast.
@nl
type
label
TFIIH and P-TEFb coordinate tr ...... pecific genes in fission yeast
@en
TFIIH and P-TEFb coordinate tr ...... ecific genes in fission yeast.
@nl
prefLabel
TFIIH and P-TEFb coordinate tr ...... pecific genes in fission yeast
@en
TFIIH and P-TEFb coordinate tr ...... ecific genes in fission yeast.
@nl
P2093
P2860
P921
P1433
P1476
TFIIH and P-TEFb coordinate tr ...... pecific genes in fission yeast
@en
P2093
Adam Rosebrock
Chao Zhang
Courtney V St Amour
Janet K Leatherwood
Jasmina J Allen
Kevan M Shokat
Laia Viladevall
Robert P Fisher
Susanne Schneider
P2860
P304
P356
10.1016/J.MOLCEL.2009.01.029
P50
P577
2009-03-01T00:00:00Z