Transforming growth factor-beta signaling: emerging stem cell target in metastatic breast cancer? - Wikidata - wikimedia - TriplyDB

Transforming growth factor-beta signaling: emerging stem cell target in metastatic breast cancer?

Transforming growth factor-beta signaling: emerging stem cell target in metastatic breast cancer?

http://www.wikidata.org/entity/Q37219226

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Interaction of tumor cells with the microenvironment Epithelial to Mesenchymal Transition in a Clinical Perspective Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway Identification of Aberrant Chromosomal Regions in Human Breast Cancer Using Gene Expression Data and Related Gene Information.The cancer stem cell concept in progression of head and neck cancer.Two faces of TGF-beta1 in breast cancer.In situ proteomic analysis of human breast cancer epithelial cells using laser capture microdissection: annotation by protein set enrichment analysis and gene ontology TGF-beta biology in mammary development and breast cancer.Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells.Tumor-fibroblast interactions stimulate tumor vascularization by enhancing cytokine-driven production of MMP9 by tumor cells.Targeting the Transforming Growth Factor-beta pathway inhibits human basal-like breast cancer metastasis.RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells.Characterization of murine pituitary-derived cell lines Tpit/F1, Tpit/E and TtT/GF.Expression of TGF-beta signaling factors in invasive breast cancers: relationships with age at diagnosis and tumor characteristics.Disabled-2 downregulation promotes epithelial-to-mesenchymal transition Colorectal cancer migration and invasion initiated by microRNA-106a Tackling the cancer stem cells - what challenges do they pose?A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland Strong impact of TGF-β1 gene polymorphisms on breast cancer risk in Indian women: a case-control and population-based study.Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma.The regulation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumor promotion by estradiol in female A/J mice Oncolytic adenovirus expressing soluble TGFβ receptor II-Fc-mediated inhibition of established bone metastases: a safe and effective systemic therapeutic approach for breast cancer.Transforming growth factor-β, insulin-like growth factor I/insulin-like growth factor I receptor and vascular endothelial growth factor-A: prognostic and predictive markers in triple-negative and non-triple-negative breast cancer.Treatment and Prevention of Bone Metastases from Breast Cancer: A Comprehensive Review of Evidence for Clinical Practice Three interrelated themes in current breast cancer research: gene addiction, phenotypic plasticity, and cancer stem cells.Mesenchymal and stemness circulating tumor cells in early breast cancer diagnosis.Involvement of gelsolin in TGF-beta 1 induced epithelial to mesenchymal transition in breast cancer cells.Bone structural components regulating sites of tumor metastasis Biological responses to TGF-β in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression.Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases Cancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas.Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGF-β1 signaling pathway Repositioning chloroquine and metformin to eliminate cancer stem cell traits in pre-malignant lesions.Luminal breast cancer metastasis is dependent on estrogen signaling.Optimal management of bone metastases in breast cancer patients.Concurrent trastuzumab and HER2/neu-specific vaccination in patients with metastatic breast cancer Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis Pharmacotherapy of triple-negative breast cancer.Role of TGF-β in breast cancer bone metastases.

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Transforming growth factor-beta signaling: emerging stem cell target in metastatic breast cancer?

http://www.wikidata.org/entity/Q37219226

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scientific article published on 09 October 2008

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Transforming growth factor-bet ...... t in metastatic breast cancer?

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Transforming growth factor-bet ...... t in metastatic breast cancer?

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Transforming growth factor-bet ...... t in metastatic breast cancer?

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Transforming growth factor-bet ...... t in metastatic breast cancer?

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Transforming growth factor-bet ...... t in metastatic breast cancer?

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Breast Cancer Research and Treatment

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Transforming growth factor-bet ...... t in metastatic breast cancer?

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Antoinette R Tan

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Michael Reiss

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The Hallmarks of Cancer

Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways

Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

The epithelial-mesenchymal transition generates cells with properties of stem cells

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

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s10549-008-0184-1

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scholarly article

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10.1007/S10549-008-0184-1

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