Functional roles of the human cytomegalovirus essential IE86 protein.
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Bioactive Molecules Released From Cells Infected with the Human CytomegalovirusThe p53-microRNA-34a axis regulates cellular entry receptors for tumor-associated human herpes viruses.Glutamine metabolism is essential for human cytomegalovirus infectionBiphasic recruitment of transcriptional repressors to the murine cytomegalovirus major immediate-early promoter during the course of infection in vivoHuman cytomegalovirus immediate-early protein promotes survival of glioma cells through interacting and acetylating ATF5Enhancerless cytomegalovirus is capable of establishing a low-level maintenance infection in severely immunodeficient host tissues but fails in exponential growth.Antagonistic determinants controlling replicative and latent states of human cytomegalovirus infectionFunctional properties of the human cytomegalovirus IE86 protein required for transcriptional regulation and virus replicationPhorbol ester-induced human cytomegalovirus major immediate-early (MIE) enhancer activation through PKC-delta, CREB, and NF-kappaB desilences MIE gene expression in quiescently infected human pluripotent NTera2 cells.The cellular protein MCM3AP is required for inhibition of cellular DNA synthesis by the IE86 protein of human cytomegalovirusTranslational control of the abundance of cytoplasmic poly(A) binding protein in human cytomegalovirus-infected cellsAlternative splicing of the human cytomegalovirus major immediate-early genes affects infectious-virus replication and control of cellular cyclin-dependent kinase.Interaction network of proteins associated with human cytomegalovirus IE2-p86 protein during infection: a proteomic analysis.Human cytomegalovirus pUL79 is an elongation factor of RNA polymerase II for viral gene transcription.Host-viral effects of chromatin assembly factor 1 interaction with HCMV IE2Mutation of glutamine to arginine at position 548 of IE2 86 in human cytomegalovirus leads to decreased expression of IE2 40, IE2 60, UL83, and UL84 and increased transcription of US8-9 and US29-32.The human cytomegalovirus UL133-138 gene locus attenuates the lytic viral cycle in fibroblasts.Association between human cytomegalovirus infection and histone acetylation level in various histological types of glioma.Infection of vascular endothelial cells with human cytomegalovirus under fluid shear stress reveals preferential entry and spread of virus in flow conditions simulating atheroprone regions of the artery.An endogenous accelerator for viral gene expression confers a fitness advantage.A short cis-acting motif in the M112-113 promoter region is essential for IE3 to activate M112-113 gene expression and is important for murine cytomegalovirus replicationAn intein-mediated modulation of protein stability system and its application to study human cytomegalovirus essential gene function.Transactivation of cellular genes involved in nucleotide metabolism by the regulatory IE1 protein of murine cytomegalovirus is not critical for viral replicative fitness in quiescent cells and host tissuesTwo Polypyrimidine Tracts in Intron 4 of the Major Immediate Early Gene Are Critical for Gene Expression Switching from IE1 to IE2 and for Replication of Human CytomegalovirusThe CREB site in the proximal enhancer is critical for cooperative interaction with the other transcription factor binding sites to enhance transcription of the major intermediate-early genes in human cytomegalovirus-infected cells.Chromatin-mediated regulation of cytomegalovirus gene expression.The human cytomegalovirus major immediate-early proteins as antagonists of intrinsic and innate antiviral host responses.Expression of Oncogenic Alleles Induces Multiple Blocks to Human Cytomegalovirus Infection.The 6-Aminoquinolone WC5 inhibits different functions of the immediate-early 2 (IE2) protein of human cytomegalovirus that are essential for viral replication.Sulfated derivatives of Escherichia coli K5 capsular polysaccharide are potent inhibitors of human cytomegalovirus.Human cytomegalovirus IE2 86 and IE2 40 proteins differentially regulate UL84 protein expression posttranscriptionally in the absence of other viral gene products.Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells.Fate-Regulating Circuits in Viruses: From Discovery to New Therapy Targets.The Canonical Immediate Early 3 Gene Product pIE611 of Mouse Cytomegalovirus Is Dispensable for Viral Replication but Mediates Transcriptional and Posttranscriptional Regulation of Viral Gene ProductsTranscription of true late (γ2) cytomegalovirus genes requires UL92 function that is conserved among beta- and gammaherpesviruses.Human cytomegalovirus infection of langerhans-type dendritic cells does not require the presence of the gH/gL/UL128-131A complex and is blocked after nuclear deposition of viral genomes in immature cells.Human Cytomegalovirus IE2 86 kDa Protein Induces STING Degradation and Inhibits cGAMP-Mediated IFN-β Induction.Murine cytomegalovirus major immediate-early protein 3 interacts with cellular and viral proteins in viral DNA replication compartments and is important for early gene activationHuman cytomegalovirus early protein pUL21a promotes efficient viral DNA synthesis and the late accumulation of immediate-early transcripts.Importance of covalent and noncovalent SUMO interactions with the major human cytomegalovirus transactivator IE2p86 for viral infection.
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Functional roles of the human cytomegalovirus essential IE86 protein.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on January 2008
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Functional roles of the human cytomegalovirus essential IE86 protein.
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Functional roles of the human cytomegalovirus essential IE86 protein.
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Functional roles of the human cytomegalovirus essential IE86 protein.
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Functional roles of the human cytomegalovirus essential IE86 protein.
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Functional roles of the human cytomegalovirus essential IE86 protein.
@en
Functional roles of the human cytomegalovirus essential IE86 protein.
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P1476
Functional roles of the human cytomegalovirus essential IE86 protein.
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P2093
D T Petrik
M F Stinski
P304
P577
2008-01-01T00:00:00Z