Antivirulence as a new antibacterial approach for chemotherapy.
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Small-Molecule Inhibitors of the Type III Secretion SystemInhibition of Staphyloxanthin Virulence Factor Biosynthesis in Staphylococcus aureus : In Vitro, in Vivo, and Crystallographic Results †Newly Discovered and Characterized Antivirulence Compounds Inhibit Bacterial Mono-ADP-Ribosyltransferase ToxinsCrystal Structures of SlyA Protein, a Master Virulence Regulator of Salmonella, in Free and DNA-bound StatesCharacterization of an Actin-targeting ADP-ribosyltransferase from Aeromonas hydrophilaNMR structure-based optimization of Staphylococcus aureus sortase A pyridazinone inhibitors.Newer antibacterial drugs for a new century.The bacterial defensin resistance protein MprF consists of separable domains for lipid lysinylation and antimicrobial peptide repulsion.The association of virulence factors with genomic islandsNew genes of Xanthomonas citri subsp. citri involved in pathogenesis and adaptation revealed by a transposon-based mutant libraryUsing small molecules to dissect mechanisms of microbial pathogenesis.Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus.Steps toward broad-spectrum therapeutics: discovering virulence-associated genes present in diverse human pathogens.Subinhibitory concentrations of thymol reduce enterotoxins A and B and alpha-hemolysin production in Staphylococcus aureus isolates.Novel Inhibitors of E. coli RecA ATPase Activity.Bile acid-induced virulence gene expression of Vibrio parahaemolyticus reveals a novel therapeutic potential for bile acid sequestrants.Postgenomic strategies in antibacterial drug discovery.Probing bacterial pathogenesis with genetics, genomics, and chemical biology: past, present, and future approaches.Exposure to Umbelliferone Reduces Ralstonia solanacearum Biofilm Formation, Transcription of Type III Secretion System Regulators and Effectors and Virulence on Tobacco.NTBC treatment of the pyomelanogenic Pseudomonas aeruginosa clinical isolate PA1111 inhibits pigment production and increases sensitivity to oxidative stressCapsaicin protects mice from community-associated methicillin-resistant Staphylococcus aureus pneumoniaDiscovery of potential anti-infectives against Staphylococcus aureus using a Caenorhabditis elegans infection model.Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?Inhibitory Effect of Dodonaea viscosa var. angustifolia on the Virulence Properties of the Oral Pathogens Streptococcus mutans and Porphyromonas gingivalis.An assessment of the future impact of alternative technologies on antibiotics markets.Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.Active-site dynamics of SpvC virulence factor from Salmonella typhimurium and density functional theory study of phosphothreonine lyase catalysis.Morin Attenuates Streptococcus suis Pathogenicity in Mice by Neutralizing Suilysin Activity.Novel agents to inhibit microbial virulence and pathogenicity.Protein export systems of Mycobacterium tuberculosis: novel targets for drug development?Proteomic signatures in antibiotic research.Multivalent glycoconjugate syntheses and applications using aromatic scaffolds.Feast or famine: the host-pathogen battle over amino acids.The post-antibiotic era: promising developments in the therapy of infectious diseases.The renaissance of bacillosamine and its derivatives: pathway characterization and implications in pathogenicity.Subterfuge and sabotage: evasion of host innate defenses by invasive gram-positive bacterial pathogens.Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence-blocking compounds.Anti-virulence Strategies to Target Bacterial Infections.Chinese herb medicine against Sortase A catalyzed transformations, a key role in gram-positive bacterial infection progress.The development of small-molecule modulators for ClpP protease activity.
P2860
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P2860
Antivirulence as a new antibacterial approach for chemotherapy.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 17 July 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Antivirulence as a new antibacterial approach for chemotherapy.
@en
Antivirulence as a new antibacterial approach for chemotherapy.
@nl
type
label
Antivirulence as a new antibacterial approach for chemotherapy.
@en
Antivirulence as a new antibacterial approach for chemotherapy.
@nl
prefLabel
Antivirulence as a new antibacterial approach for chemotherapy.
@en
Antivirulence as a new antibacterial approach for chemotherapy.
@nl
P1476
Antivirulence as a new antibacterial approach for chemotherapy.
@en
P2093
Sonia Escaich
P304
P356
10.1016/J.CBPA.2008.06.022
P577
2008-07-17T00:00:00Z