PEG-rIL-10 treatment decreases FoxP3(+) Tregs despite upregulation of intratumoral IDO

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Prognostic value of tumor infiltrating lymphocyte subsets in breast cancer depends on hormone receptor status.Oral IL-10 suppresses colon carcinogenesis via elimination of pathogenicCD4+ T-cells and induction of antitumor CD8+ T-cell activity.

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PEG-rIL-10 treatment decreases FoxP3(+) Tregs despite upregulation of intratumoral IDO

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 27 June 2016

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PEG-rIL-10 treatment decreases FoxP3

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PEG-rIL-10 treatment decreases FoxP3(+) Tregs despite upregulation of intratumoral IDO

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PEG-rIL-10 treatment decreases FoxP3

@nl

PEG-rIL-10 treatment decreases FoxP3(+) Tregs despite upregulation of intratumoral IDO

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PEG-rIL-10 treatment decreases FoxP3

@nl

PEG-rIL-10 treatment decreases FoxP3(+) Tregs despite upregulation of intratumoral IDO

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PEG-rIL-10 treatment decreases FoxP3(+) Tregs despite upregulation of intratumoral IDO

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Brett Jorgenson

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Harminder Bal

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John B Mumm

http://www.w3.org/2001/XMLSchema#string

Melissa Bilardello

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Peter Van Vlasselaer

http://www.w3.org/2001/XMLSchema#string

Scott McCauley

http://www.w3.org/2001/XMLSchema#string

Victoria Wu

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Treatment of Crohn's disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon gamma

IDO expression by dendritic cells: tolerance and tryptophan catabolism

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group.

Interleukin 10 treatment of psoriasis: clinical results of a phase 2 trial.

Essential role of nitric oxide and interferon-gamma for tumor immunotherapy with interleukin-10.

IL-10 directly acts on T cells by specifically altering the CD28 co-stimulation pathway.

Proinflammatory effects of IL-10 during human endotoxemia.

A molecular basis for T cell suppression by IL-10: CD28-associated IL-10 receptor inhibits CD28 tyrosine phosphorylation and phosphatidylinositol 3-kinase binding.

Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohn's Disease IL-10 Cooperative Study Group.

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e1197458

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scholarly article

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10.1080/2162402X.2016.1197458

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http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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Ivan H Chan

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2016-06-27T00:00:00Z

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27622052

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5006922

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PEG-rIL-10 treatment decreases FoxP3(+) Tregs despite upregulation of intratumoral IDO

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PEG-rIL-10 treatment decreases FoxP3(+) Tregs despite upregulation of intratumoral IDO

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P1476

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