Host-directed drug targeting of factors hijacked by pathogens.
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Identification and characterization of the role of c-terminal Src kinase in dengue virus replicationLeishmania Infection Engages Non-Receptor Protein Kinases Differentially to Persist in Infected HostsShedding light on filovirus infection with high-content imagingA metabolic network approach for the identification and prioritization of antimicrobial drug targetsStructural genomics and drug discovery for infectious diseasesNaloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded FunctionsIdentification of host-dependent survival factors for intracellular Mycobacterium tuberculosis through an siRNA screenPotent host-directed small-molecule inhibitors of myxovirus RNA-dependent RNA-polymerasesA screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hitIdentification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysisThe landscape of host transcriptional response programs commonly perturbed by bacterial pathogens: towards host-oriented broad-spectrum drug targetsChemical derivatives of a small molecule deubiquitinase inhibitor have antiviral activity against several RNA virusesIdentification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growthNovel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosisSecretome: clues into pathogen infection and clinical applications.Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase RSensitization of intracellular Salmonella enterica serovar Typhimurium to aminoglycosides in vitro and in vivo by a host-targeted antimicrobial agent.Acetalated dextran encapsulated AR-12 as a host-directed therapy to control Salmonella infection.Eradication of intracellular Salmonella enterica serovar Typhimurium with a small-molecule, host cell-directed agentSystematic approaches towards the development of host-directed antiviral therapeutics.Small molecule inhibitors of the host cell COX/AREG/EGFR/ERK pathway attenuate cytomegalovirus-induced pathogenesisMycobacterium tuberculosis metabolismCritical role for phosphoinositide 3-kinase gamma in parasite invasion and disease progression of cutaneous leishmaniasis.Replication-Competent Influenza Virus and Respiratory Syncytial Virus Luciferase Reporter Strains Engineered for Co-Infections Identify Antiviral Compounds in Combination Screens.CMV-induced embryonic mouse organ of corti dysplasia: Network architecture of dysfunctional lateral inhibition.New Role for FDA-Approved Drugs in Combating Antibiotic-Resistant BacteriaTargeting Batf2 for infectious diseases and cancer.Cytosolic sulfotransferase 1A1 regulates HIV-1 minus-strand DNA elongation in primary human monocyte-derived macrophages.Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection.Proteomics of bacterial pathogenicity: therapeutic implications.Cancer and viruses: a double-edged sword.Mutation rate and the emergence of drug resistance in Mycobacterium tuberculosis.Approaches targeting the type III secretion system to treat or prevent bacterial infections.Host-Directed Therapies for Tuberculosis.Update on the Development of Anti-Viral Agents Against Hepatitis C.Genome Expression Profiling-Based Identification and Administration Efficacy of Host-Directed Antimicrobial Drugs against Respiratory Infection by Nontypeable Haemophilus influenzae.Polymerases of paramyxoviruses and pneumoviruses.Dual myxovirus screen identifies a small-molecule agonist of the host antiviral response.Identification of a broad-spectrum inhibitor of viral RNA synthesis: validation of a prototype virus-based approach.Klebsiella pneumoniae targets an EGF receptor-dependent pathway to subvert inflammation.
P2860
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Host-directed drug targeting of factors hijacked by pathogens.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 22 July 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Host-directed drug targeting of factors hijacked by pathogens.
@en
Host-directed drug targeting of factors hijacked by pathogens.
@nl
type
label
Host-directed drug targeting of factors hijacked by pathogens.
@en
Host-directed drug targeting of factors hijacked by pathogens.
@nl
prefLabel
Host-directed drug targeting of factors hijacked by pathogens.
@en
Host-directed drug targeting of factors hijacked by pathogens.
@nl
P356
P1433
P1476
Host-directed drug targeting of factors hijacked by pathogens.
@en
P2093
Anita Schwegmann
Frank Brombacher
P356
10.1126/SCISIGNAL.129RE8
P577
2008-07-22T00:00:00Z