Beyond prostaglandins--chemistry and biology of cyclic oxygenated metabolites formed by free-radical pathways from polyunsaturated fatty acids.
about
Rearrangements of organic peroxides and related processesLipid profiling following intake of the omega 3 fatty acid DHA identifies the peroxidized metabolites F4-neuroprostanes as the best predictors of atherosclerosis preventionLipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipidsOxidative Stress Biomarkers: Establishment of Reference Values for Isoprostanes, AOPP, and NPBI in Cord Blood.Docosahexaenoic acid metabolome in neural tumors: identification of cytotoxic intermediates.Oxysterols from free radical chain oxidation of 7-dehydrocholesterol: product and mechanistic studies.Synthesis of a bicyclobutane fatty acid identified from the cyanobacterium Anabaena PCC 7120Current development in non-enzymatic lipid peroxidation products, isoprostanoids and isofuranoids, in novel biological samples.Measurement of F2- isoprostanes and isofurans using gas chromatography-mass spectrometry.Unraveling curcumin degradation: autoxidation proceeds through spiroepoxide and vinylether intermediates en route to the main bicyclopentadione.Isoprostane generation and function.Facile synthesis of cyclopentenone B1- and L1-type phytoprostanesIsoprostanes and 4-hydroxy-2-nonenal: markers or mediators of disease? Focus on Rett syndrome as a model of autism spectrum disorder.Analytical variables affecting analysis of F2-isoprostanes and F4-neuroprostanes in human cerebrospinal fluid by gas chromatography/mass spectrometry.A divergent synthesis of the delta(13)-9-isofurans.An azido-biotin reagent for use in the isolation of protein adducts of lipid-derived electrophiles by streptavidin catch and photorelease.The role of oxidative stress in Rett syndrome: an overview.Quantitative metabolic profiling of lipid mediators.Biosynthesis and analysis of plant oxylipins.Unresolved issues in the analysis of F2-isoprostanes, F4-neuroprostanes, isofurans, neurofurans, and F2-dihomo-isoprostanes in body fluids and tissue using gas chromatography/negative-ion chemical-ionization mass spectrometry.Highly functionalized and potent antiviral cyclopentane derivatives formed by a tandem process consisting of organometallic, transition-metal-catalyzed, and radical reaction steps.Simultaneous quantitative profiling of 20 isoprostanoids from omega-3 and omega-6 polyunsaturated fatty acids by LC-MS/MS in various biological samples.The effects of long (C20/22) and short (C18) chain omega-3 fatty acids on keel bone fractures, bone biomechanics, behavior, and egg production in free-range laying hens.Free radical oxidation of polyunsaturated lipids: New mechanistic insights and the development of peroxyl radical clocks.Catalytic asymmetric formal synthesis of beraprost.Measurement of urinary F(2)-isoprostanes by gas chromatography-mass spectrometry is confounded by interfering substances.Synthesis of epoxyisoprostanes: effects in reducing secretion of pro-inflammatory cytokines IL-6 and IL-12.Regulation of [³H]d-aspartate release by the 5-F(2t)-isoprostane and its 5-epimer in isolated bovine retina.Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins.Total syntheses and in vivo quantitation of novel neurofuran and dihomo-isofuran derived from docosahexaenoic acid and adrenic acid.Total syntheses of all tri-oxygenated 16-phytoprostane classes via a common precursor constructed by oxidative cyclization and alkyl-alkyl coupling reactions as the key steps.A practical synthesis of chiral tricyclic cyclopenta[b]benzofuran, a key intermediate of Beraprost.Oxygenated metabolites of n-3 polyunsaturated fatty acids as potential oxidative stress biomarkers: total synthesis of 8-F3t-IsoP, 10-F4t-NeuroP and [D4]-10-F4t-NeuroP.Synthesis and discovery of phytofurans: metabolites of α-linolenic acid peroxidation.Synthesis of Bioconjugate Sesterterpenoids with Phospholipids and Polyunsaturated Fatty Acids.Synthesis, Discovery, and Quantitation of Dihomo-Isofurans: Biomarkers for In Vivo Adrenic Acid Peroxidation
P2860
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P2860
Beyond prostaglandins--chemistry and biology of cyclic oxygenated metabolites formed by free-radical pathways from polyunsaturated fatty acids.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Beyond prostaglandins--chemist ...... m polyunsaturated fatty acids.
@en
Beyond prostaglandins--chemist ...... m polyunsaturated fatty acids.
@nl
type
label
Beyond prostaglandins--chemist ...... m polyunsaturated fatty acids.
@en
Beyond prostaglandins--chemist ...... m polyunsaturated fatty acids.
@nl
prefLabel
Beyond prostaglandins--chemist ...... m polyunsaturated fatty acids.
@en
Beyond prostaglandins--chemist ...... m polyunsaturated fatty acids.
@nl
P2093
P356
P1476
Beyond prostaglandins--chemist ...... m polyunsaturated fatty acids.
@en
P2093
Jean-Marie Galano
Thierry Durand
Ullrich Jahn
P304
P356
10.1002/ANIE.200705122
P407
P577
2008-01-01T00:00:00Z