Combining naltrexone and prazosin in a single oral medication decreases alcohol drinking more effectively than does either drug alone.
about
A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction.The Combination of Marketed Antagonists of α1b-Adrenergic and 5-HT2A Receptors Inhibits Behavioral Sensitization and Preference to Alcohol in Mice: A Promising Approach for the Treatment of Alcohol DependenceCombining the α1 -adrenergic receptor antagonist, prazosin, with the β-adrenergic receptor antagonist, propranolol, reduces alcohol drinking more effectively than either drug alone.Chronic treatment with prazosin or duloxetine lessens concurrent anxiety-like behavior and alcohol intake: evidence of disrupted noradrenergic signaling in anxiety-related alcohol use.The α2-adrenergic receptor agonist, clonidine, reduces alcohol drinking in alcohol-preferring (P) rats.Naltrexone and prazosin combination for posttraumatic stress disorder and alcohol use disorder.Low-dose prazosin alone and in combination with propranolol or naltrexone: effects on ethanol and sucrose seeking and self-administration in the P rat.Prazosin Reduces Alcohol Intake in an Animal Model of Alcohol Relapse.Prazosin + Naltrexone Decreases Alcohol Drinking More Effectively Than Does Either Drug Alone in P Rats with a Protracted History of Extensive Voluntary Alcohol Drinking, Dependence, and Multiple Withdrawals.Prazosin reduces alcohol drinking throughout prolonged treatment and blocks the initiation of drinking in rats selectively bred for high alcohol intake.Rat animal models for screening medications to treat alcohol use disorders.Influence of stress associated with chronic alcohol exposure on drinking.Combining Varenicline (Chantix) with Naltrexone Decreases Alcohol Drinking More Effectively Than Does Either Drug Alone in a Rodent Model of Alcoholism.Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone.V1b Receptor Antagonist SSR149415 and Naltrexone Synergistically Decrease Excessive Alcohol Drinking in Male and Female Mice.Varenicline Reduces Alcohol Intake During Repeated Cycles of Alcohol Reaccess Following Deprivation in Alcohol-Preferring (P) Rats.Co-Administration of Low-Dose Naltrexone and Bupropion Reduces Alcohol Drinking in Alcohol-Preferring (P) Rats.Involvement of activated brain stress responsive systems in excessive and "relapse" alcohol drinking in rodent models: implications for therapeutics.A Combination of Naltrexone + Varenicline Retards the Expression of a Genetic Predisposition Toward High Alcohol Drinking.
P2860
Q28068256-FC3B0AE9-C943-4CE6-862C-082024525066Q28550709-6F5AD84A-33A0-494B-B4B3-571A94AFD033Q33719351-7621837A-D74A-4DC9-BE0D-7BF67F79CBFAQ34025026-505C4C5C-6AD3-4494-8719-BF59632AEB7DQ34175631-17626CD9-7998-4152-B213-1432A9EF755AQ35054242-AA457624-D2C6-4E27-A48D-3AA072826589Q35858582-1E9B3C89-8940-4591-933D-EEFBD652F407Q35891252-A8FD20ED-27AD-4A36-8EAD-9CA45A02FC17Q36021630-982A6021-DF33-44C3-9F73-ED1F7159967AQ37179376-8821ABB2-22CA-4332-9A65-19851E0EED95Q39142990-270F54E2-3C8A-454A-9E9A-1FF138B92671Q39255467-B2290B32-C92A-4B53-A250-F91D0DF801B2Q42149212-C4C89C47-8FE8-4043-A6DF-4D838BC9079FQ44343754-C703D9AD-4CB1-4A2D-8CDF-2A39A003761BQ47589467-B5DFD587-E779-44E4-9D81-84C12EBB03B1Q48004085-367FDCDF-C52D-4667-BD10-B008237B00DAQ48148853-44480D22-0C54-4E7F-B133-FA24C65EBF19Q52317998-948FF239-E88F-46CA-81FA-100B1D210C93Q54998102-425592BE-4D75-4B9F-B00C-169E23188782
P2860
Combining naltrexone and prazosin in a single oral medication decreases alcohol drinking more effectively than does either drug alone.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 22 July 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Combining naltrexone and prazo ...... y than does either drug alone.
@en
Combining naltrexone and prazo ...... y than does either drug alone.
@nl
type
label
Combining naltrexone and prazo ...... y than does either drug alone.
@en
Combining naltrexone and prazo ...... y than does either drug alone.
@nl
prefLabel
Combining naltrexone and prazo ...... y than does either drug alone.
@en
Combining naltrexone and prazo ...... y than does either drug alone.
@nl
P2093
P2860
P356
P1476
Combining naltrexone and prazo ...... y than does either drug alone.
@en
P2093
Brett J Hausauer
Dennis D Rasmussen
Janice C Froehlich
P2860
P304
P356
10.1111/ACER.12148
P577
2013-07-22T00:00:00Z