CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion
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Chemokine receptor-specific antibodies in cancer immunotherapy: achievements and challengesCancer stem cells in basic science and in translational oncology: can we translate into clinical application?ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuitTargeting CXCR1/CXCR2 receptor antagonism in malignant melanomaInterleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid [MMA(III)]-induced malignant transformation of urothelial cellsOverexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer.An artificial miRNA against HPSE suppresses melanoma invasion properties, correlating with a down-regulation of chemokines and MAPK phosphorylation.Leu128(3.43) (l128) and Val247(6.40) (V247) of CXCR1 are critical amino acid residues for g protein coupling and receptor activation.Glioblastoma cell-secreted interleukin-8 induces brain endothelial cell permeability via CXCR2An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.GPCRs and cancerThe role of chemoattractant receptors in shaping the tumor microenvironment.CXCL7-Mediated Stimulation of Lymphangiogenic Factors VEGF-C, VEGF-D in Human Breast Cancer CellsCXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesisThe emerging role of CXC chemokines and their receptors in cancer.A systems biology approach reveals common metastatic pathways in osteosarcoma.CXCR1 and CXCR2 silencing modulates CXCL8-dependent endothelial cell proliferation, migration and capillary-like structure formation.Role of chemokine receptor CXCR2 expression in mammary tumor growth, angiogenesis and metastasis.The prognostic value of CXC-chemokine receptor 2 (CXCR2) in gastric cancer patients.CXCR2 expression and postoperative complications affect long-term survival in patients with esophageal cancer.T-Cadherin Expression in Melanoma Cells Stimulates Stromal Cell Recruitment and Invasion by Regulating the Expression of Chemokines, Integrins and Adhesion Molecules.Upregulation of C-X-C chemokine receptor type 1 expression is associated with late-stage gastric adenocarcinomaModulation of CXCL-8 expression in human melanoma cells regulates tumor growth, angiogenesis, invasion, and metastasisExpression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significanceRepertaxin, an inhibitor of the chemokine receptors CXCR1 and CXCR2, inhibits malignant behavior of human gastric cancer MKN45 cells in vitro and in vivo and enhances efficacy of 5-fluorouracilHost Cxcr2-dependent regulation of mammary tumor growth and metastasisHuman pituitary tumor-transforming gene 1 overexpression reinforces oncogene-induced senescence through CXCR2/p21 signaling in breast cancer cells.CXCR2 Inhibition in Human Pluripotent Stem Cells Induces Predominant Differentiation to Mesoderm and Endoderm Through Repression of mTOR, β-Catenin, and hTERT Activities.Silencing of CXCR2 and CXCR7 protects against esophageal cancerLow expression of CXCR1/2 on neutrophils predicts poor survival in patients with hepatitis B virus-related acute-on-chronic liver failure.IL-8 promotes HNSCC progression on CXCR1/2-meidated NOD1/RIP2 signaling pathway.CXCL8 and its cognate receptors in melanoma progression and metastasis.The prognostic significance of heparanase expression in metastatic melanomaNovel approaches to treating leptomeningeal metastases.Differential Expression of Chemokine Receptors and their Roles in Cancer Imaging.Angiogenesis, vasculogenic mimicry and vascular invasion in cutaneous malignant melanoma - implications for therapeutic strategies and targeted therapies.Chemokines in cancer development and progression and their potential as targeting molecules for cancer treatment.Angiogenesis in melanoma: an update with a focus on current targeted therapies.Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasisThe chemokine receptors CXCR1 and CXCR2 regulate oral cancer cell behaviour.
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P2860
CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion
@en
CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion.
@nl
type
label
CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion
@en
CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion.
@nl
prefLabel
CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion
@en
CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion.
@nl
P2093
P2860
P356
P1476
CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.BJC.6605055
P407
P577
2009-04-28T00:00:00Z