GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme.
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Spore photoproduct lyase: the known, the controversial, and the unknownIdentification of a unique radical S-adenosylmethionine methylase likely involved in methanopterin biosynthesis in Methanocaldococcus jannaschii.Mechanistic diversity of radical S-adenosylmethionine (SAM)-dependent methylation.Delineating the biosynthesis of gentamicin x2, the common precursor of the gentamicin C antibiotic complex.Consecutive radical S-adenosylmethionine methylations form the ethyl side chain in thienamycin biosynthesisThe thiostrepton A tryptophan methyltransferase TsrM catalyses a cob(II)alamin-dependent methyl transfer reaction.Investigation of enzymatic C-P bond formation using multiple quantum HCP nuclear magnetic resonance spectroscopyThe enzyme-mediated direct reversal of a dithymine photoproduct in germinating endosporesOn the Role of Additional [4Fe-4S] Clusters with a Free Coordination Site in Radical-SAM Enzymes.Radical S-adenosylmethionine enzymes.Molecular architectures and functions of radical enzymes and their (re)activating proteins.Aminoglycoside Antibiotics: New Insights into the Biosynthetic Machinery of Old Drugs.Parallel pathways in the biosynthesis of aminoglycoside antibiotics.Vitamin B12 in the spotlight again.Biosynthesis of Branched Alkoxy Groups: Iterative Methyl Group Alkylation by a Cobalamin-Dependent Radical SAM Enzyme.Initial characterization of Fom3 from Streptomyces wedmorensis: The methyltransferase in fosfomycin biosynthesis.A B12-dependent radical SAM enzyme involved in oxetanocin A biosynthesis.Spectroscopic characterization and mechanistic investigation of P-methyl transfer by a radical SAM enzyme from the marine bacterium Shewanella denitrificans OS217.The B12-Radical SAM Enzyme PoyC Catalyzes Valine Cβ-Methylation during Polytheonamide Biosynthesis.Specificity and promiscuity at the branch point in gentamicin biosynthesis.Radical SAM Enzymes in the Biosynthesis of Ribosomally Synthesized and Post-translationally Modified Peptides (RiPPs).Methyltransferases of gentamicin biosynthesis.TsrM as a Model for Purifying and Characterizing Cobalamin-Dependent Radical S-Adenosylmethionine Methylases.Efficient methylation of C2 in l-tryptophan by the cobalamin-dependent radical S-adenosylmethionine methylase TsrM requires an unmodified N1 amine.Reaction Catalyzed by GenK, a Cobalamin-Dependent Radical S-Adenosyl-l-methionine Methyltransferase in the Biosynthetic Pathway of Gentamicin, Proceeds with Retention of Configuration.Reconstitution and Substrate Specificity of the Radical S-Adenosyl-methionine Thiazole C-Methyltransferase in Thiomuracin Biosynthesis.Mechanism of a Class C Radical S-Adenosyl-l-methionine Thiazole Methyl Transferase.An Engineered Tryptophan Synthase Opens New Enzymatic Pathways to β-Methyltryptophan and Derivatives.d-Sedoheptulose-7-phosphate is a common precursor for the heptoses of septacidin and hygromycin B.Biosynthesis of antibiotic chuangxinmycin from Actinoplanes tsinanensis.
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GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 21 May 2013
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vedecký článok
@sk
vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
GenK-catalyzed C-6' methylatio ...... -dependent radical SAM enzyme.
@en
GenK-catalyzed C-6' methylatio ...... -dependent radical SAM enzyme.
@nl
type
label
GenK-catalyzed C-6' methylatio ...... -dependent radical SAM enzyme.
@en
GenK-catalyzed C-6' methylatio ...... -dependent radical SAM enzyme.
@nl
prefLabel
GenK-catalyzed C-6' methylatio ...... -dependent radical SAM enzyme.
@en
GenK-catalyzed C-6' methylatio ...... -dependent radical SAM enzyme.
@nl
P2093
P2860
P356
P1476
GenK-catalyzed C-6' methylatio ...... n-dependent radical SAM enzyme
@en
P2093
Hak Joong Kim
Hung-wen Liu
Jake LeVieux
Reid M McCarty
Steven O Mansoorabadi
Yung-nan Liu
P2860
P304
P356
10.1021/JA312641F
P407
P577
2013-05-21T00:00:00Z